王臺，桐柏縣人，中國科學院植物研究所研究員，中科院博士研究生導師，首席研究員，分子發育生物學研究中心主任助理。
個人經歷
中國科學院植物研究所研究員
河南省桐柏縣人，中科院博士研究生導師，首席研究員，分子發育生物學研究中心主任助理。
研究方向及領域
研究方向：植物分子生理學，蛋白質組學
研究領域
小孢子與花粉發育的分子機制：主要興趣是了解花粉功能特異性的分子基礎與調控機制、花粉單倍體基因組的特點以及該基因組如何調控花粉管的極性生長。
減數分裂的分子機制：減數分裂是有性生殖的關鍵環節，在減數分裂過程中同源染色體的同源重組是形成生物遺傳多樣性的基礎。我們的工作重點是解析植物減數分裂同源染色體聯會、重組與分離的機制，為植物育性的調控提供新基因與新知識。
功能蛋白質組學研究：通過功能蛋白質組學研究，揭示由單倍體花粉發育的機制、花粉與雌蕊細胞識別與通訊的分子基礎等重要的生物學問題。同時，為認識花粉過敏等與人類健康相關的一些問題奠定基礎。我們也在探索利用功能蛋白質組學的技術體系解析淀粉代謝的調控等問題。
工作經歷
1988年在武漢大學獲碩士學位；
1993年至1994年在日本東京大學和大坂大學工作學習；
1997年在中國科學院植物研究所獲博士學位；
1997年至1998年在日本原子能研究所作訪問學者。
學術任職
中國科學院植物研究所首席研究員、中國科學院大學教授、中國植物學會副秘書長、中國植物學會植物生理與分子生物學專業委員會副主任、中科院光合作用與環境分子生理學院重點實驗室學術委員會委員。兼任《植物學通報》副主編、《Journal of Integrative Plant Biology》編委。
承擔項目
主持和承擔中國科學院重要方向性項目1項，“973”三級課題2項，“863”課題2項，國家轉基因植物與產業化課題1項，國家自然科學基金項目3項。
主要研究
1.花粉發育分子生理機制
利用功能蛋白質組和基因組學手段，結合細胞學、生理學等證據探討水稻花粉減數分裂與花粉發育的機制，揭示遺傳和表觀遺傳調控重要的蛋白質的功能。
2．種子發育分子生理機制
利用種子突變體，通過遺傳、細胞和生理學研究探討調控種子大小與形狀的分子機制，結合功能蛋白質組分析，揭示相關的蛋白質網絡。
主持和參加的科研項目：
“水稻OsUBP1蛋白的生化特性與生理功能分析”，國家自然科學基金課題（批準號：30570147）（2006.1-2008.12），25萬元，主持人。
“水稻種子發育的蛋白組研究”，國家重大科學研究計劃項目“重要組織和細胞的動態蛋白質組學研究”課題（批準號：2006CB910105）（2006.10-2010.12），483萬元，主持人。
“水稻內質網、高爾基體與液泡功能蛋白質組研究”，中國科學院知識創新工程重要方向性項目（批準號：KSCX2-YW-N-026）(2006.10-2009.12)，100萬元，首席科學家。
“SAR基因的克隆與功能分析”，水稻863重大項目子課題(批準號：2006AA10A101)（2006.12-2010.10），75萬元，主持人。
“組蛋白甲基化修飾重要調控蛋白質的蛋白質組解析”，國家重大科學研究計劃項目“植物表觀遺傳機制與重要調控蛋白質的功能和結構研究”課題（批準號：2012CB910504）（2012.01-2015.12），350萬元，主持人。
主要論文
[1] Chenshan Xu, Bingtang Chen, Shanjin Huang, Zhuyun Deng, Tai Wang. Apoint mutation in the rice alpha-tubulin gene OsTUBA3 causes grain notching. The New Phytologist[J]. 2023, 240: 1052-1065, [2] Zhuyun Deng, Yuxia Liu, Chunyan Gong, Bingtang Chen, Tai 汪姓 Waxy is an important factor for grain fissure resistance and head rice yield as revealed by a genome-wide association study. Journal of Experimental 植物學[J]. 2022, 73(19): 6942-6954.
[3] Song, Yunyun, Tang, Yongyan, Liu, Lingtong, Xu, Yunyuan, Wang, Tai. The 甲基CpG-binding domain family member PEM1 is essential for Ubisch body formation and pollen exine development in rICE PLANT JOURNAL[J]. 2022, 111(5): 1283-1295.
[4] Liu, Lingtong, Wang, Tai. Male 配子體 development in flowering plants: A story of quarantine and sacrifice. JOURNAL OF PLANT PHYSIOLOGYnull. 2021, 258.
[5] Lu, Yunlong, Song, Yunyun, Liu, Lingtong, Wang, Tai. 脫氧核糖核酸 methylation 動力學 of sperm 細胞 lineage development in 柑仔蜜 PLANT JOURNAL[J]. 2021, 105(3): 565-579.
[6] Yang, Fan, Wang, Tai, Liu, Lingtong. Pollen germination is impaired by disruption of a Shaker K+ channel OsAKT1.2 in rice. JOURNAL OF PLANT PHYSIOLOGY[J]. 2020, 248.
[7] Yu, Bo, Liu, Lingtong, Wang, Tai. Deficiency of very long chain alkanes biosynthesis causes humidity-sensitive male sterility via affecting pollen adhesion and hydration in rice. PLANT CELL AND ENVIRONMENT[J]. 2019, 42(12): 3340-3354.
[8] Han, Bing, Yang, Ning, Pu, Hai, Wang, Tai. Quantitative Proteomics and Cytology of Rice Pollen 固醇Rich Membrane Domains Reveals Pre-established Cell 極性 Cues in Mature Pollen. JOURNAL OF PROTEOME RESEARCH[J]. 2018, 17(4): 1532-1546.
[9] Liu, Lingtong, Lu, Yunlong, Wei, Liqin, Yu, Hua, Cao, Yinghao, Li, Yan, Yang, Ning, Song, Yunyun, Liang, Chengzhi, Wang, Tai. Transcriptomics analyses reveal the molecular roadmap and long non-coding 核糖核酸 landscape of sperm 細胞 lineage development. PLANT JOURNAL[J]. 2018, 96(2): 421-437.
[10] WangTai. Protein isolation from 等離子體 membrane, digestion and processing for strong cation exchange fractionation. Bio-protocol. 2017.
[11] WangTai. Plasma membrane preparation from Lilium davidii and Oryza sativa mature and germinated pollen. Bio-protocol. 2017.
[12] Yang, Ning, Wang, Tai. Comparative proteomic analysis reveals a dynamic pollen 等離子體 membrane protein map and the membrane landscape of 捕手-like kinases and transporters important for pollen tube growth and interaction with pistils in rice. BMC PLANT BIOLOGY[J]. 2017, 17(1).
[13] Yu, Huatao, Wang, Tai. Proteomic Dissection of Endosperm Starch Granule Associated Proteins Reveals a Network Coordinating Starch Biosynthesis and 氨基 Acid 新陳代謝 and Glycolysis in Rice Endosperms. FRONTIERS IN PLANT SCIENCE[J]. 2016, 7(-).
[14] Li, Qi, Deng, Zhuyun, Gong, Chunyan, Wang, Tai. The Rice Eukaryotic Translation Initiation Factor 3 Subunit f (OseIF3f) Is Involved in Microgametogenesis FRONTIERS IN PLANT SCIENCE[J]. 2016, 7(-).
[15] Liu, Lingtong, Zheng, Canhui, Kuang, Baijan, Wei, Liqin, Yan, Longfeng, Wang, Tai. 捕手Like Kinase RUPO Interacts with 鉀 Transporters to Regulate Pollen Tube Growth and Integrity in Rice. PLOS GENETICS[J]. 2016, 12(7).
[16] Yang, Hao, Yang, Ning, Wang, Tai. Proteomic analysis reveals the differential histone programs between male germline cells and vegetative cells in Lilium davidii. PLANT JOURNAL[J]. 2016, 85(5): 660-674.
[17] Lu, Yunlong, Wei, Liqin, Wang, Tai. Methods to isolate a large amount of generative cells, sperm cells and vegetative nuclei from 柑仔蜜 pollen for "omics" analysis. FRONTIERS IN PLANT SCIENCE[J]. 2015, 6.
[18] Deng, Zhu Yun, Liu, Ling Tong, Li, Tang, Yan, Song, Kuang, Bai Jian, Huang, Shan Jin, Yan, Chang Jie, Wang, Tai. OsKinesin-13A Is an Active Microtubule Depolymerase Involved in Glume Length Regulation via Affecting Cell Elongation. SCIENTIFIC REPORTS[J]. 2015, 5(-).
[19] Agrawal, 迦乃士 Kumar, Job, Dominique, Kieselbach, Thomas, Barkla, Bronwyn J, Chen, Sixue, Deswal, Renu, Luethje, Sabine, Amalraj, Ramesh Sundar, Tanou, Georgia, Ndimba, Bongani Kaiser, Cramer, Rainer, Weckwerth, Wolfram, Wienkoop, Stefanie, Dunn, Michael J, Kim, Sun Tae, Fukao, Yochiro, Yonekura, Masami, Zolla, Lello, Rohila, Jai Singh, WaditeeSirisattha, Rungaroon, Masi, Antonio, Wang, Tai, Sarkar, Abhijit, Agrawal, Raj, Renaut, Jenny, Rakwal, Randeep. INPPO Actions and Recognition as a Driving Force for Progress in Plant Proteomics: Change of Guard, INPPO Update, and Upcoming Activities. PROTEOMICS[J]. 2013, 13(21): 3093-310.
[20] Deng, Zhu Yun, Gong, Chun Yan, Wang, Tai. Use of proteomics to understand seed development in rice. PROTEOMICS[J]. 2013, 13(12-13): 1784-1800.
[21] Gong, Chun Yan, Wang, Tai. Proteomic evaluation of genetically modified crops: current status and challenges. FRONTIERS IN PLANT SCIENCEnull. 2013, 4.
[22] Zhao, Xin, Yang, Ning, Wang, Tai. Comparative Proteomic Analysis of Generative and Sperm Cells Reveals Molecular Characteristics Associated with Sperm Development and 函數 Specialization. JOURNAL OF PROTEOME RESEARCH[J]. 2013, 12(11): 5058-5071.
[23] Yu, Hua Tao, Xu, Sheng Bao, Zheng, Can Hui, Wang, Tai. Comparative Proteomic Study Reveals the Involvement of Diurnal Cycle in 細胞 Division, Enlargement, and Starch Accumulation in Developing Endosperm of Oryza sativa. JOURNAL OF PROTEOME RESEARCH[J]. 2012, 11(1): 359-371.
[24] Wang, Zizhang, Yan, Shijuan, Liu, Chunming, Chen, Fang, Wang, Tai. Proteomic Analysis Reveals an 黃曲霉毒素Triggered Immune Response in Cotyledons of 落花生屬 hypogaea Infected with Aspergillus flavus. JOURNAL OF PROTEOME RESEARCH[J]. 2012, 11(5): 2739-2753.
[25] Gong, Chun Yan, Li, Qi, Yu, Hua Tao, Wang, Zizhang, Wang, Tai. Proteomics Insight into the Biological Safety of Transgenic Modification of Rice As Compared with Conventional Genetic Breeding and Spontaneous Genotypic Variation. JOURNAL OF PROTEOME RESEARCH[J]. 2012, 11(5): 3019-3029.
[26] Wang, Zizhang, Wang, Tai. Dynamic proteomic analysis reveals diurnal homeostasis of key pathways in rice Leaves PROTEOMICS[J]. 2011, 11(2): 225-238.
[27] Wei, Li Qin, Yan, Long Feng, Wang, Tai. Deep sequencing on genome-wide scale reveals the unique composition and expression patterns of microRNAs in developing pollen of Oryza sativa. GENOME BIOLOGY[J]. 2011, 12(6): R53-R53.
[28] An, Xiao Jing, Deng, Zhu Yun, Wang, Tai. OsSpo11-4, a Rice 同系物 of the Archaeal TopVIA Protein, Mediates Double-Strand 脫氧核糖核酸 Cleavage and Interacts with OsTopVIB. PLOS ONE[J]. 2011, 6(5).
[29] Bing Han, Sixue Chen, Shaojun Dai, Ning Yang, Tai Wang. Isobaric Tags for Relative and Absolute Quantificationbased Comparative Proteomics Reveals the Features of 等離子體 Membrane-Associated Proteomes of Pollen Grains and Pollen Tubes from Lilium davidii. 植物學報：英文版[J]. 2010, 1043-1058.
[30] Wei, Li Q, Xu, Wen Y, Deng, Zhu Y, Su, Zhen, Xue, Yongbiao, Wang, Tai. Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa. BMC GENOMICS[J]. 2010, 11(2): 338-338.
[31] Xu, Sheng Bao, Yu, Hua Tao, Yan, Long Feng, Wang, Tai. Integrated Proteomic and Cytological Study of Rice Endosperms at the Storage Phase. JOURNAL OF PROTEOME RESEARCH[J]. 2010, 9(10): 4906-4918.
[32] Zhao, Lifeng, Hu, Yibing, Chong, Kang, Wang, Tai. ARAG1, an ABA-responsive DREB gene, plays a role in seed germination and drought tolerance of rice. ANNALS OF 植物學[J]. 2010, 105(3): 401-409.
[33] Li, Tang, Gong, Chunyan, Wang, Tai. RA68 is required for postmeiotic pollen development in Oryza sativa. PLANT MOLECULAR BIOLOGY[J]. 2010, 72(3): 265-277.
[34] Hu, Yibing, Zhao, Lifeng, Chong, Kang, Wang, Tai. Overexpression of OsER一級方程式錦標賽, a novel rice ERF gene, up-regulates 乙烯responsive genes expression besides affects growth and development in Arabidopsis. JOURNAL OF PLANT PHYSIOLOGY[J]. 2008, 165(16): 1717-1725.
[35] Xu, Sheng Bao, Li, Tang, Deng, Zhu Yun, Chong, Kang, Xue, Yongbiao, Wang, Tai. Dynamic proteomic analysis reveals a switch between central 碳 新陳代謝 and alcoholic 發酵 in rice filling grains. PLANT PHYSIOLOGY[J]. 2008, 148(2): 908-925.
[36] Deng, ZhuYun, Wang, Tai. OsDMC1 is required for homologous pairing in Oryza sativa. PLANT MOLECULAR BIOLOGY[J]. 2007, 65(1-2): 31-42.
[37] Jiayi Tao, Liangran Zhang, Kang Chong, Tai Wang. OsRAD21-3, an orthologue of 酵母浸膏 RAD21, is required forpollen development in Oryza sativa. THE PLANT JOURNAL[J]. 2007, 51(5): 919-930.
[38] WangTai. Proteomic identification of differentially expressed proteins associated with pollen germination and tube growth reveals characteristics of germinated Oryza sativa pollen. MOLECULAR AND CELLULAR PROTEOMICS. 2007.
[39] Dai, S, Li, L, Chen, T, Chong, K, Xue, Y, Wang, T. Proteomic analyses of Oryza sativa mature pollen reveal novel proteins associated with pollen germination and tube growth. PROTEOMICS[J]. 2006, 6(8): 2504-2529.
參考資料：
參考資料 >
王臺.-.2016-02-29
王臺.中國科學院大學.2024-08-30