吳建國，1981年出生于池州市，福建農(nóng)林大學(xué)教授，博士研究生導(dǎo)師。現(xiàn)任福建農(nóng)林大學(xué)植物保護(hù)學(xué)院媒介病毒研究中心執(zhí)行主任、教授。
人物經(jīng)歷
2010-2016年于北京大學(xué)生命科學(xué)學(xué)院李毅教授和清華大學(xué)生命學(xué)院戚益軍教授實(shí)驗(yàn)室從事博士后研究工作，并榮獲北京大學(xué)-清華大學(xué)生命科學(xué)聯(lián)合中心優(yōu)秀博士后、羅氏優(yōu)秀博士。
人物成就
主要從事水稻抗病毒和病毒致病相關(guān)研究，其研究成果在eLife, Nature Plants, PLoS 病原體和Molecular Plant等雜志上發(fā)表SCI論文20篇，累計(jì)影響因子＞100，5年內(nèi)文章累計(jì)被引用近500次。
主持國家自然科學(xué)基金優(yōu)秀青年基金、面上基金、“973”和“863”計(jì)劃項(xiàng)目子課題的研究。擔(dān)任中植物病理學(xué)會(huì)植物與病原互作委員會(huì)秘書長、中國植物病理學(xué)會(huì)青年學(xué)術(shù)委員會(huì)副主任、Annals of Phytopathology編委、《激光生物學(xué)報(bào)》常務(wù)編委等。
所獲榮譽(yù)
吳建國教授獲得多項(xiàng)榮譽(yù)，包括：
- 2020年8月11日，入選國家自然科學(xué)基金委員會(huì)公布的2020年度國家杰出青年科學(xué)基金建議資助項(xiàng)目申請人名單；
- 2021年2月1日，被授予“第十五屆福建青年科技獎(jiǎng)”稱號(hào)；
- 國家優(yōu)秀青年基金獲得者；
- 霍英東基金獲得者；
- 中國植物病理學(xué)會(huì)-青年植物病理學(xué)家獎(jiǎng)獲得者；
- 福建省中國青年五四獎(jiǎng)?wù)?/a>獲得者；
- 嚴(yán)家顯最高獎(jiǎng)教金獲得者；
- 福建農(nóng)林大學(xué) “金山學(xué)者”拔尖人才；2012年獲福建省“優(yōu)秀博士論文二等獎(jiǎng)”；
- 2013年入選福建省高校杰出青年科研人才培育計(jì)劃;
- 2014年入選福建省青年拔尖人才；
- 2017年福建省新世紀(jì)優(yōu)秀人計(jì)劃；
- 2018年福建省領(lǐng)軍人才-拔尖人才。
研究方向
1. 基于核糖核酸沉默的水稻抗病毒和病毒致病機(jī)制；
2. Small RNA的跨界（昆蟲病毒植物界微生物）調(diào)控；
3. 病毒與宿主的相互作用以及病毒對宿主發(fā)育的影響；
4. 水稻抗病毒資源的篩選和抗病毒基因的克隆。
科研項(xiàng)目
- 2020年國家杰出青年基金項(xiàng)目；
- 2019年國家自然基金海峽聯(lián)合基金重點(diǎn)項(xiàng)目；
- 2018年福建省高校領(lǐng)軍人才-拔尖人才項(xiàng)目；
- 2017年國家優(yōu)秀國家自然科學(xué)基金青年科學(xué)基金項(xiàng)目管理辦法；
- 2017年國家自然基金面上項(xiàng)目；
- 2012年國家自然基金面上項(xiàng)目。
發(fā)表論文
1） Shanshan Zhao, Yuansheng Wu, Jianguo Wu. Arms race between rice and viruses: an review of viral proteins and 植物界 factors. Current Opinion in Virology, 2021,47:38–44.
（2） Lu Wang, Huiting Xie, Xiaoyuan Zheng, Jiasheng Chen, Shuai Zhang, Jianguo 吳語 Recent advances and emerging trends in antiviral defence networking in rice. The Crop Journal, 2021,Revision.
（3） Shuai Zhang, Xiaoqing Wu , Huiting Xie, Shanshan Zhao, Jianguo Wu. Multifaceted roles of 核糖核酸 polymerase IV in 植物界 growth and development, Journal of Experimental 植物學(xué)，2020, 71(19): 5725–5732.
（4） Chao Zhang, Ying Wei, Le Xu, Kangcheng Wu, Liang Yang, Chaonan Shi, Guoyi Yang, Dong Chen, Feifei Yu, Qi Xie, Yi Li, Shouwei Ding, Jianguo 吳語 A Bunya病毒Inducible Ubiquitin Ligase Targets 核糖核酸 Polymerase IV for Degradation during Viral 病程 in Rice, Molecular 植物界, 2020, 13(6):836-850.
（5） Le Xu, Kun Yuan, Meng Yuan, Xiangbing Meng, Min Chen, Jianguo Wu, Jiayang Li, Yijun Qi. Regulation of Rice Tillering by 核糖核酸directed 脫氧核糖核酸 Methylation at Miniature Inverted-repeat Transposable Elements, Molecular 植物界, 2020, 13(6)851-863.
（6） Chao Zhang, Dong Chen, Guoyi Yang, Xiyuan Yu, Jianguo Wu. Rice Stripe Mosaic 病毒-encoded P4 Is A Weak Suppressor of Viral 核糖核酸 Silencing and is Required for Disease Symptom Development. Molecular 植物界Microbe Interactions, 2020, 33(3):412-422.
（7） Jiaqi Qin, Ci Wang, Leqi Wang, Shanshan Zhao and Jianguo 吳語 Defense and counter-defense in rice–病毒 interactions. Phytopathology Research, 2019,1:34.
（8） Baogang Zhang, Wenji Li, Jialin Zhang, Lu Wang and Jianguo Wu. Roles of small RNAs in virus-植物界 interactions. Viruses, 2019, 11(9), 827.
（9） Shengze Yao, Zhirui Yang, Rongxin Yang, Yu Huang, Ge Guo, Xiangyue Kong, Ying 藍(lán)姓, Tong Zhou, He Wang, Wenming Wang, Xiaofeng Cao, Jianguo Wu, Yi Li. Transcriptional regulation of miR528 by OsSPL9 orchestrates antiviral response in rice. Molecular 植物界, 2019,12(8):1114-1122.
（10） Lijia Zheng, Chao Zhang, Jianguo Wu and Yi Li.Detecting the interaction of double-stranded 核糖核酸 binding protein, viral protein and primary miRNA transcript by co-immunoprecipitation in 植物界Bio-protocol, 2018, 8,09, 2840.
（11） Chao Zhang, Chaonan Shi, 越南盾 Chen and Jianguo 吳語Rice ragged stunt 病毒 propagation and infection on rice plants. Bio-protocol, 2018, 8,20, 3060.
（12） Zhaoyun Wang, Yeqiang Xia, Siyuan Lin, Yanru Wang, Baohuan Guo, Xiaoning Song, Shaochen Ding, Liyu Zheng, Ruiying Feng, Shulin Chen, Yalin Bao, Cong Sheng, Xin Zhang,Jianguo Wu, Dongdong Niu, Hailing Jin and Hongwei Zhao. Osa-miR164a targets OsNAC60 and negatively regulates rice 免疫力 against the blast fungus Magnaporthe oryzae. The 植物界 Journal, 2018, 95(4): 584-597.
（13） Jianguo Wu, Rongxin Yang, Zhirui Yang, Shengze Yao, Shanshan Zhao, Yu Wang, Pingchuan Li, Xianwei Song, Lian Jin, Tong Zhou, Ying 藍(lán)姓, Lianhui Xie, Xueping Zhou, Chengcai Chu, Yijun Qi, Xiaofeng Cao and Yi Li. ROS accumulation and antiviral defence 監(jiān)察 by microRNA528 in rice. Nature Plants, 2017, 3, 16203. （高被引論文）
（14） Shanshan Zhao, Wei Hong, Jianguo Wu, Yu Wang, Shaoyi Ji, Shuyi Zhu, Chunhong Wei, Jinsong Zhang, Yi Li, A viral protein promotes 宿主 SAMS1 activity and 乙烯 production for the benefit of 病毒 infection. eLife, 2017,6:e27529.
（15） Lijia Zheng, Chao Zhang, Chaonan Shi, Zhirui Yang, Yu Wang, Tong Zhou, Feng Sun, Hong Wang, Shanshan Zhao, Qingqing Qin, Rui Qiao, Zuomei Ding, Chunhong Wei, Lianhui Xie, Jianguo Wu, Yi Li. Rice stripe 病毒 NS3 protein regulates primary miRNA processing through association with the miRNA biogenesis factor OsDRB1 and facilitates virus infection in rice.PLoS 病原體, 2017,13(10): e1006662.
（16） Chao Zhang, Zuomei Ding, Kangcheng Wu, Liang Yang, Yang Li, Zhen Yang, Shan Shi, Xiaojuan Liu, Shanshan Zhao, Zhirui Yang, Yu Wang, Luping Zheng, Juan Wei, Zhenguo Du, Aihong Zhang, Hongqin Miao, Yi Li, Zujian Wu andJianguo 吳語Suppression of jasmonic acid-mediated defense by viral-inducible microRNA319 facilitates 病毒 infection in rice.Molecular 植物界, 2016, 9:1372-1384.
（17） Lian Jin, Qingqing Qin, Yu Wang, Yingying Pu, Lifang Liu, Xing Wen, Shaoyi Ji,Jianguo Wu, Chunhong Wei, Biao Ding and Yi Li. Rice dwarf 病毒 P2 protein hijacks auxin signaling by directly targeting the rice OsIAA10 protein, enhancing viral infection and disease development. PLOS 病原體,2016, 12(9): e1005847.
（18） Jianguo Wu, Zhirui Yang, Yu Wang, Lijia Zheng, Ruiqiang Ye, Yinghua Ji, Shanshan Zhao, Shaoyi Ji, Ruofei Liu, Le Xu, Hong Zheng, Yijun Zhou, Xin Zhang, Xiaofeng Cao, Lianhui Xie, Zujian Wu, Yijun Qi and Yi Li. Viral-inducible 船蛸18 confers broad-spectrum 病毒 厚膜電阻 in rice by sequestering a 宿主 microRNA. eLife,2015, 4:e05733.
（19） Chao Zhang, Xiaojuan Liu, Kangcheng Wu, Luping Zheng, Zuomei Ding, Fei Li, Peng Zou, Liang Yang, Jianguo Wu and Zujian 吳語 Rice grassy stunt virus nonstructural protein p5 serves as a viral suppressor of 核糖核酸 silencing and interacts with nonstructural protein p3.Archives of 病毒學(xué), 2015, 160(11): 2769-2779.
（20） Chao Zhang, Zujian Wu Yi Li and Jianguo Wu.Biogenesis, function and applications of 病毒derived small RNAs in plants.Frontiers in Microbiology, 2015, 6:1237.
（21） Luping Zheng, Zhenguo Du,Chen Lin, Qianzhuo Mao, Kangcheng Wu, Jianguo Wu, Taiyun Wei, Zujian Wu and Lianhui Xie.Rice stripe tenuivirus p2 may recruit or manipulate nucleolar functions through an Interaction with fibrillarin to promote 病毒 systemic movement. Molecular 植物界 病理學(xué), 2015,16 (9): 921–930.
（22） Liang Yang, Zhenguo Du, Feng Gao, Kangcheng Wu, Lianhui Xie, Yi Li, Zujian Wu and Jianguo 吳語Transcriptome profiling confirmed correlations between symptoms and transcriptional changes in RDV infected rice and revealed 核仁 as a possible target of RDV manipulation.病毒學(xué) Journal, 2014, 11:81.
（23） Jang-Kyun Seo,Jianguo Wu, Yifan Lii, Yi Li and Hailing Jin.Contribution of small 核糖核酸 神經(jīng)通路 components in 植物界 免疫力Molecular Plant-Microbe Interactions, 2013, 26(6):617-25.
（24） Peng Du, Jianguo Wu, Jiayao Zhang, Shuqi Zhao, Hong Zheng, Ge Gao, Liping Wei and Yi Li. Viral infection induces expression of novel phased microRNAs from conserved cellular microRNA precursors. PLoS 病原體, 2011,7(8): e1002176.
（25） Zhenguo Du, Donglai Xiao,Jianguo Wu, Dongsheng Jia, Zhengjie Yuan, Ying Liu, Liuyang Hu, Zhao Han, Taiyun Wei, Qiying Lin, Zujian Wuand Lianhui Xie. P2 of Rice stripe 病毒 (RSV) interacts with OsSGS3 and is a silencing suppressor.Molecular 植物界 病理學(xué),2011, 12(8):808-14.
（26） Jianguo Wu, Chunzheng Wang, Zhengguo Du, Lijun Cai, Meiqun Hu, Zujian Wu, Yi Liand Lianhui Xie.Identification of Pns12 as the second silencing suppressor of rice gall dwarf 病毒 Science China Life Sciences,2011,54 (3): 201-208.
（27） Jianguo Wu, Zhenguo Du, Chunzheng Wang, Lijun Cai, Meiqun Hu, Qiying Lin, Zujian Wu, Yi Li and Lianhui Xie. Identification of Pns6, a putative movement protein of RRSV, as a silencing suppressor. 病毒學(xué) Journal, 2010, 7:335.
（28） Zujian Wu,JianguoWu, Scott Adkins, Lianhui Xie and Weimin Li. Rice ragged stunt 病毒 線段 S6-encoded nonstructural protein Pns6 complements cell-to-細(xì)胞 movement of tobacco mosaic virus-based chimeric virus. Virus Research, 2010,152:176-179.
（29） Chunzheng Wang, Feng Gao, Jianguo Wu,Jianli Dai, Chunhong Wei and Yi Li.Arabidopsis Putative Deacetylase AtSRT2 Regulates Basal Defense by Suppressing PAD4, EDS5 and SID2 Expression.Plant andCell 生理學(xué),2010, 51(8): 1291-1299.
（30） Junwei Guo, Fangli Ren,Yinyin Wang, Shan Li, Zhengrong Gao, Xiaoyan Wang, Hongxiu Ning, Jianguo Wu, Yi Li, Zhao Wang, Shek Man Chim, Jiake Xu and Zhijie Chang.miR-764-5p promotes osteoblast differentiation through 性抑制 of 晶片/STUB1 expression.Journal of Bone and Mineral Research, 2012, 27(7):1607–1618 IF: 7.056.
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