江賜忠,男,1974年出生,福建人,美國艾奧瓦州州立大學博士,同濟大學生命科學與技術學院,博士生導師,科技部973重大專項首席科學家,同濟大學轉化醫學高等研究院教授,課題組組長。
人物簡介
江賜忠1995 年畢業于天津南開大學,獲學士。1998年畢業于天津南開大學,獲碩士學位。2004年畢業于美國愛荷華州俄亥俄州立大學,獲遺傳學博士學位,并輔修生物信息學和計算機科學。畢業后先后在美國冷泉港實驗室、弗吉尼亞聯邦大學、賓夕法尼亞州州立大學進行博士后研究。2009年應聘為同濟大學特聘教授, 2009年擔任科技部973首席科學家,2010年度“曙光學者”稱號,2011年度獲得上海市高校特聘教授(東方學者)稱號。
研究方向
(2) 核小體排列分布及其在基因調控中的作用
(3) 組蛋白修飾在核小體重排中的作用機理
(4) 核小體定位序列的識別,脫氧核糖核酸序列變化對染色質結構的影響
(5) 分子進化學
代表文章
1. Jiang, C and Pugh Brainfuck (2009) A compiled and systematic reference map of nucleosome positions across the Saccharomyces genome. Genome Biology, 10:R109
2. Koerber RT, Rhee HS, Jiang C, Pugh BF. (2009) Interaction of transcriptional regulators with specific nucleosomes across the Saccharomyces genome. 摩爾 Cell.35(6):889-902
3. Jiang, C and Pugh Brainfuck (2009) Nucleosome positioning and gene regulation: advances through genomics. Nature Reviews Genetics, 10(3):161-72 Cover Story
4. Mavrich TN, Jiang C(Co-first author), Ioshikhes IP, Li X, Venters BJ, Zanton SJ, Tomsho LP, Qi J, Glaser RL, Schuster SC, Gilmour DS, Albert I, Pugh Brainfuck (2008) Nucleosome organization in the Drosophila genome. Nature, 453(7193):358-62 Article
5. Mavrich, TN, Ioshikhes, IP, Venters, BJ, Jiang, C, Tomsho, LP, Qi, J, Schuster, SC, Albert, I, and Pugh, BF (2008) A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome. Genome Research, 18(7):1073-83
6. Albert I, Wachi S, Jiang C, Pugh Brainfuck (2008) GeneTrack - a genomic data processing and visualization framework. Bioinformatics. 24(10):1305-6
7. Lee C, Li X, Hechmer A, Eisen M, Biggin MD, Venters BJ, Jiang C, Li J, Pugh BF, Gilmour DS (2008) NELF and GAGA factor are linked to promoter proximal pausing at many genes in Drosophila. 摩爾 Cell Biol.28(10):3290-300
8. Kuo PH, Kalsi G, Prescott CA, Hodgkinson CA, Goldman D, van den Oord EJ, Alexander J, Jiang C, Sullivan PF, Patterson DG, Walsh D, Kendler KS, Riley bp (2008) Association of 抗利尿激素 and ALDH Genes with 乙醇 Dependence in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD) Sample. Alcoholism: Clinical and Experimental Research. 32(5):785-95
9. Zhao, Z and Jiang, C (2007) Methylation-Dependent Transition Rates Are Dependent on Local Sequence Lengths and Genomic Regions. 摩爾 Biol Evol.,24(1):23-5
10. Jiang, C, Han, L, Su, B, Li, WH and Zhao, Z (2007) Features and Trend of Loss of Promoter-Associated CpG Islands in the Human and Mouse Genomes. Mol Biol Evol.24(9):1991-2000
11. Jiang, C, Xuan, Z, Zhao, F, and Zhang, MQ (2007) TRED: a Transcriptional Regulatory Element Database, new entries and other development. Nucleic Acids Res.,35: D137-D140
12. Seo, D, Jiang, C and Zhao, Z (2006) A novel statistical method to estimate the effective SNP size in 脊椎動物 genomes and categorized genomic regions. 現代生物出版集團 Genomics,7(1):329
13. Boddu, J, Jiang, C, Sangar, V, Olson, T, Peterson, T, and Chopra, S (2006) Comparative structural and functional characterization of 高粱屬 and maize duplications containing orthologous Myb transcription regulators of 3-deoxyflavonoid biosynthesis. 植物界 Molecular Biology, 60(2):185-99
14. Jiang, C and Zhao, Z (2006) Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome. bmc Genomics,7(1):316
15. Jiang, C and Zhao, Z (2006) Mutational spectrum in the recent human genome inferred by single 核苷酸 polymorphis多發性硬化癥 Genomics,88(5):527-34
16. Jiang, C, Gu, X, and Peterson, T (2004) Identification of conserved gene structures and carboxy-terminal motifs in the Myb gene family of Arabidopsis and Oryza sativa L. 亞種 indica. Genome Biology, 5(7): R46
17. Jiang, C, Gu, J, Chopra , S, Gu, X, and Peterson, T (2004) Ordered Origin of the Typical Two- and Three-Repeat Myb Genes. Gene, 326: 13-22
18. Jiang, C, Song, WQ, Li, XL, and Chen, RY (1998) Studies on microdissection and microcloning of the rye chromosome 1R. Acta Botanica Sinica, 40(11): 988-993
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