譚保才，2018年6月任山東大學青島校區副校長兼生命科學學院院長。泰山學者海外特聘專家。1997年獲得佛羅里達大學（University ofFlorida）植物分子遺傳學博士學位，獲佛羅里達大學1997年度最佳博士學位論文獎；曾任香港中文大學生物系研究副教授、香港中文大學深圳研究院教授。
正文
教育背景
起止時間 學位 畢業院校 專業
1992/09 - 1997/06 博士 佛羅里達大學（美國）植物分子遺傳學
1984/09 - 1987/06 碩士 蘭州大學 植物生理學
1980/09 - 1984/06 學士 蘭州大學 植物生理學
工作經歷
2013/12 - 至 今 山東大學生命科學學院 特聘教授，院長，泰山區學者
2011/01 - 2013/12 香港中文大學深圳研究院 研究員
2007/12 - 2013/12 香港中文大學植物分子與農業技術研究所 研究副教授
2001/03 - 2007/12 佛羅里達大學癌癥與遺傳研究所 研究助理教授
1997/07 - 2001/02 佛羅里達大學植物分子與細胞生物學 博士后
1992/08 - 1997/06 佛羅里達大學園藝科學系 研究助理
1987/06 - 1992/08 蘭州大學生物系 講師
主要成果
科研方向
課題組主要以玉米為模式植物研究種子發育的分子遺傳調控機制。種子發育與糧食作物的產量和品質密切相關，解析種子發育的分子遺傳調控機制既是植物學的一個根本問題，也是農業生產高產優質育種的重要基礎。種子發育過程涉及復雜的遺傳調控網絡，突變體是解析遺傳網絡組成元件的主要遺傳材料。我們利用Mutator轉座子分離了大量的玉米種子發育突變體，開發了針對性的基因克隆技術，通過基因克隆和遺傳學、分子生物學和細胞生物學分析，查明這些基因的分子功能，解析調控種子發育的分子機制和調控網絡，為分子育種提供理論基礎。目前為止，實驗室克隆了40多個玉米籽粒發育關鍵基因，通過功能解析，揭示了調控種子發育的重要途徑并創新了相關的基礎理論，如確立了植物激素ABA是通過間接途徑合成；發現了一個前所未知的阿魏屬酰蔗糖循環途徑；該循環介導單子葉植物中細胞壁木聚糖阿魏酰化；初步解析了細胞器核糖核酸編輯和內含子剪接的機制，為后續研究奠定了基礎。其中，關于ABA合成途徑的研究成果被編入美國《Plant Physiology》（Taiz&Zaiger ed.）大學教材，并被翻譯成中文等語言。實驗室參與構建的UniformMu突變體庫供全球科學家使用，成為玉蜀黍屬遺傳學研究最重要的資源。
參考資料：
目前的研究課題
1，植物細胞器RNA加工的機制解析：通過分子遺傳鑒定參與細胞器RNA編輯、內含子剪接和成熟的基因，解析編輯體、內含子剪接蛋白復合體的組成和作用機制；
2，禾本科細胞壁木聚糖阿魏屬酰化的分子機制研究：完善阿魏酰蔗糖循環途徑及探索阿魏酰化程度對主要農藝性狀的影響和調控；
3，玉米種子發育關鍵新基因的挖掘和功能鑒定：利用實驗室的突變體庫挖掘影響種子發育新基因并解析功能。
參考資料：
主持課題
2023-2027，國家自然科學基金重點項目，玉米細胞壁木聚糖阿魏酰化的分子機制研究。
2018-2019，國家自然科學基金重大研究計劃重點項目，玉米籽粒大小主要遺傳網絡的解析和分子機制研究。
2017-2021，國家自然科學基金重點項目，玉米種子發育關鍵PPR基因的功能和作用機理研究。
2015-2017，國家自然科學基金重大研究計劃重點項目，玉米籽粒形成關鍵基因的克隆和生物學功能分析。
2014-2016，Hong Kong RGC，Functional analysis of SMALL KERNEL 11 and identification of its interacting proteins.
2013-2015，Hong Kong RGC，Functional analysis of Empty pericarp5 in maize seed development.
2012-2015，國家自然科學基金面上項目，玉米小籽粒基因Smk2的克隆和功能分析。
2012-2014，Hong Kong RGC，Functional analysis of EMB15 in maize seed development.
2012-2016，深圳孔雀計劃（Co-PI），Applied research of plant molecular biotechnology on modern agriculture.
2010-2012，Hong Kong RGC， Genetic and functional dissection of Emb12 and Emb14 in maize embryo development.
參考資料：
主要作品
代表性研究成果
1. Yang, D., Liu, H., Li, X., Zhang, YF系列火箭發動機, Zhang, X., Yang, H., Liu, M., Koch, K.E., McCarty, D.R., Li, S., Tan, B.C.* (2024). A 蔗糖 ferulate cycle linchpin for ferulyolation of arabinoxylans in plant 鴨跖草類植物 Nature Plants DOI: 10.1038/s41477-024-01781-1.
2. Yang, Y.Z.*, Liu, X.Y., Gao, S., Zhang, S.G., Tan, B.C.* (2024). 無規共聚聚丙烯21 is involved in the splicing of nad2 introns via interacting with PPR-SMR1 and SPR2 and is essential to maize seed development. J. 獛屬 Genomics DOI: 10.1016/j.jgg2024.08.010
3. Chen, B.#, Wang, J.#, Gui, Y., Wang, L., Wei, Q., Huang, M., Tan, B.C.* (2024). C1-FDX is required for the assembly of mitochondrial complexes I and V. PLoS Genetics (in press).
4. Wang, L., Chen, B., Ma, B., Wang, Y., Wang, H., Sun, X., Tan, B.C.* (2024). Maize Dek51 encodes a DEAD-box 核糖核酸 解旋酶 essential for pre-rRNA processing and seed development. Cell Reports 43, 114673.
5. Wang, Y., Huang, Z.Q., Tian, K.D., Li, H., Xu, C., Xia, B., Tan, B.C.* (2024). 倍數 factors interact in the editing of the 無規共聚聚丙烯E+ targeted sites in maize mitochondria and plastids. Plant Commun. 5: 100836.
6. Liu X.Y., Jiang, R.C., Ma, B., Wang, Y., Yang, Y.Z., Xu, C., Sun, F., Tan, B.C.* (2024). Maize requires Embryo defective27 for embryogenesis and seedling development. Plant Physiology 195: 430-445.
7. Ma, B.#, Liu, H.#, Xiu, Z., Yang, H.H., Wang, H., Wang, Y., Tan, B.C.* (2024). Defective kernel 58 encodes an Rrp15p domain-containing protein essential to ribosome biogenesis and seed development in maize. New Phytologist 241: 1662-1675.
8. Yang Y.Z., Ding, S., Liu., X.Y., Xu, C., Sun, F., Tan, B.C.* (2023). The DEAD-box 核糖核酸 解旋酶 ZmRH48 is required for the splicing of 倍數 mitochondrial introns, mitochondrial complex biosynthesis, and seed development in maize. JIPB 65: 2456-2468.
9. Zu, X., Luo, L., Wang, Z., Gong, J., Yang, C., Deng, X., Song, X., Wang, Y., Xu, C., Qiao X., Chen, C., Tan, B.C., Cao, X.* (2023). A mitochondrial pentatricopeptide repeat protein enhances cold tolerance by modulating mitochondrial superoxide in rice. Nature Commun. 14: 6789.
10. Wang, Y., Li, H., Huang, Z.Q., Ma, B., Yang, Y.Z., Xiu, Z.H., Wang, L., Tan, B.C.* (2023). Maize 無規共聚聚丙烯E proteins mediate 核糖核酸 C-to-U editing in mitochondria by recruiting the trans deaminase PCW1. Plant Cell 35: 529–551.
11. Yang, Y.Z.#, Liu, X.Y.#, Tang, 約翰·約翰遜, Wang, Y., Xu, C., Tan, B.C.* (2022). GRP23 plays a core role in E-type editosomes via interacting with MORFs and atypical 無規共聚聚丙烯DYWs in Arabidopsis mitochondria. Proc. Natl. Acad. Sci. USA 119: e2210978119.
12. Liu, H., Xiu, Z., Yang, H., Ma, Z., Yang, D., Wang, H., Tan, B.C.* (2022). SHREK1 encoding a WD40 protein involves in ribosome biogenesis by regulating pre-rRNA processing in maize. Plant Cell 34: 4028-4044.
13. Cao, S.K.#, Liu, R.#, Wang, M., Sun, F., Sayyed, A., Shi, H., Wang, X., Tan, B.C.* (2022). (2022). Small 無規共聚聚丙烯 protein SPR2 interacts with PPR-SMR1 to facilitate the splicing of introns in maize mitochondria. Plant Physiology 190: 1763-1776.
14. Zhao, J.#, Cao, S.K.#, Li, X.L., Sun, F., Jiang, R.C., Xu, C.H., Tan, B.C.* (2022). Emp80 is required for mitochondrial nad7 and atp4 transcript editing and seed development in maize. New Phytologist 234: 1237-1248.
15. Wang F., Yu, Z., Zhang, M., Wang, M., Lu, X., Liu, X., Li, Y., Zhang, X., Tan, B.C., Li, C.*, Ding Z.* (2021). ZmTE1 promotes plant height by regulating intercalary meristem formation and internode 細胞 elongation in maize. Plant Biotechnol. J. 20: 526-537.
16. Liu, X.Y., Jiang, R.C., Wang, Y., Tang, J.J., Sun, F., Yang, Y.Z., Tan, B.C.* (2021). ZmPPR26, a DYW-type pentatricopeptide repeat protein, is required for C-to-U 核糖核酸 editing at atpA-1148 in maize chloroplasts. J. Exp. Bot. 72: 4809-4821.
17. Xu, C., Shen, Y., Li, C., Lu, F., Zhang, M.D., Meeley, R.B., McCarty, D.R. Tan, B.C.* (2021). Emb15 encodes a 質體 ribosomal assembly factor essential for embryogenesis in maize. Plant J. 106: 214-227.
18. Yang, Y.Z., Ding, S., Liu, X.Y., Tang, 約翰·約翰遜, Wang, Y., Sun, F., Xu, C., Tan, B.C.* (2021). EMP32 is required for the cis-splicing of nad7 intron 2 and seed development in maize. 核糖核酸 Biology 18: 499-509.
19. Xu, C., Song, S., Yang, Y.Z., Lu, F., Zhang, M.D., Sun, F., Jia, R., Song, R., Tan, B.C.* (2020). DEK46 performs C-to-U editing of a specific site in mitochondrial nad7 introns that is critical for intron splicing and seed development in maize. Plant J. 103: 1767-1782.
20. Liu, R., Cao, S.K., Sayyed, A., Yang, H.H., Zhao J., Wang, X.M., Jia, R.X., Sun, F., Tan, B.C.* (2020). The DYW-subgroup pentatricopeptide repeat protein 無規共聚聚丙烯27 interacts with ZmMOR一級方程式錦標賽 to facilitate mitochondrial 核糖核酸 editing and seed development in maize. J. Exp. Bot. 71: 5495-5505.
21. Wang, H.C., Sayyed, A., Liu, X.Y., Yang, Y.Z., Sun, F., Wang, Y., Wang, M.D., Tan, B.C.* (2020). SMALL KERNEL4 is required for mitochondrial cox1 transcript editing and seed development in maize. JIPB. 62: 777-792.
22. Wang Y., Liu, X.Y., Yang, Y.Z., Huang, J., Sun, F., Lin, J.S., Gu, Z.Q., Sayyed, A., Xu, C., Tan, B.C.* (2019). Empty pericarp21 encodes a novel 無規共聚聚丙烯DYW protein that is required for mitochondrial 核糖核酸 editing at multiple sites, complexes I and V biogenesis, and seed development in maize. PLoS Genetics 15(8): e1008305.
23. Chen, Z.#, Wang, H.C.#, Shen, J., Sun, F., Wang M.D. Xu, C., Tan, B.C.* (2019). 無規共聚聚丙烯SMR1 is required for the splicing of 倍數 mitochondrial introns and interacts with Zm-mCS一級方程式錦標賽 and is essential for seed development in maize. J. Exp. Bot. 70: 5245-5258.
24. Sun, F., Xiu, Z., Jiang, R., Liu, Y., Zhang, X., Yang, Y.Z., Li, X., Zhang, X., Wang, Y., Tan, B.C.* (2019). The mitochondrial pentatricopeptide repeat protein EMP12 is involved in the splicing of three nad2 introns and seed development in maize. J. Exp. Bot. 70: 963-972.
25. Li, X.L., Huang, W.L., Jiang R.C., Sun, F., Wang, H.C., Zhao, J., Xu, C., Tan, B.C.* (2019). EMP18 functions in mitochondrial atp6 and cox2 transcript editing and is essential to seed development in maize. New Phytologist 221: 896-907.
26. Sun, F., Zhang, X., Shen, Y., Wang, H., Liu, R., Wang, X., Gao, D., Yang, Y.Z., Liu, Y., Tan, B.C.* (2018). The pentatricopeptide repeat protein EMPTY PERICARP8 is required for the splicing of three mitochondrial introns and seed development in maize. Plant J. 95: 919-932.
27. Zhang YF系列火箭發動機, 鈴木公司 M., Sun F., Tan B.C.* (2017). The 線粒體targeted PENTATRICOPEPTIDE REPEAT78 protein is required for nad5 mature mRNA stability and seed development in maize. Molecular Plant 10: 1321-1333.
28. Yang Y.Z., Ding S., Wang Y., Li C.L., Shen Y., Meeley R., McCarty D.R., Tan B.C.* (2017). Small kernel2 encodes a glutaminase in Vitamin B6 biosynthesis and is essential for maize seed development. Plant Physiology 174: 1127-1138.
29. Cai M., Li S., Sun F., Sun Q., Zhao H., Ren X., Zhao Y., Tan B.C., Zhang Z.*, Qiu F.* (2017). Emp10 encodes a mitochondrial PPR protein that affects the cis-splicing of nad2 intron 1 and seed development in maize. Plant J. 91: 132-144.
30. Tan B.C., Guan J.C., Ding S., Wu S., Koch K.E., McCarty D.R.* (2017). Structure and origin of the White Cap locus and its role in the evolution of grain color in maize. Genetics 206: 135-150.
31. Yang Y.Z., Ding S., Wang H.C., Sun F., Huang W.L., Song S., Xu C.H., Tan B.C.* (2017). The pentatricopeptide repeat protein EMP9 is required for mitochondrial ccmB and rps4 transcript editing, mitochondrial complex biogenesis and seed development in maize. New Phytologist 214: 782-795.
32. Xiu Z., Sun F., Shen Y., Zhang X., Jiang R., Bonnard G., Zhang J., Tan B.C.* (2016). EMPTY PERICARP16 is required for mitochondrial nad2 intron 4 cis-splicing and seed development in maize. Plant J. 85: 507-519.
33. Li C., Shen Y., Meeley R., McCarty D.R., Tan, B.C.* (2015). Embryo defective 14 encodes a 質體targeted cGTPase essential for embryogenesis in maize. Plant J. 84: 785-799.
34. Sun F., Wang X., Bonnard G., Shen Y., Xiu Z., Li, X., Gao, D., Zhang, Z., Tan B.C.* (2015). empty pericarp 7 encodes a mitochondrial E-subgroup pentatricopeptide repeat protein that is required for ccmFN editing, mitochondrial function and seed development in maize. Plant J. 84: 283-295.
35. Chen Y., Hou M., Liu L., Wu S., Shen Y., Ishiyama K., Kobayashi M., McCarty D.R., Tan B.C.* (2014). The maize DWARF 1 encodes a Gibberellin 3-oxidase and is dual-localized to the 細胞核 and cytosol. Plant Physiology 166: 2028-2039.
36. Li X.J., Zhang Y.F., Hou M.M., Sun F., Shen Y., Xiu Z.H., Wang X.M., Chen Z.L., Sun S.S.M., Small I., Tan B.C.* (2014). Small kernel 1 encodes a pentatricopeptide repeat protein required for mitochondrial nad7 transcript editing and seed development in maize and rice. Plant J. 79: 797–809.
37. Shen Y., Li C., Meeley R., McCarty D.R., Tan B.C.* (2013). Embryo defective 12 encodes translation initiation factor 3 and is essential to maize embryogenesis. Plant J. 74: 792-804.
38. Liu Y., Xiu Z.H., Meeley R., Tan B.C.* (2013). Empty pericarp 5 encodes a pentatricopeptide repeat protein that is required for mitochondrial 核糖核酸 editing and seed development in maize. Plant Cell 25: 868-883.
39. Messing 永恒沉睡, Gabelli sb, Echeverria I., Vogel 日本煙草產業, Guan J.C., Tan B.C., Klee H.J., McCarty D.R., Amzel L.M. (2010). Structural insights into maize Viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid. Plant Cell 22: 2970-2980.
40. Vogel 日本煙草產業, Tan B.C., McCarty D.R., Klee H.J. (2008). The carotenoid cleavage dioxygenase 1 enzyme has broad substrate specificity, cleaving multiple carotenoids at two different bond positions. J. Biol. Chem. 283: 11364-1137.
41. McCarty D.R., Settles A.M., Suzuki M., Tan B.C., Latshaw S., Porch T., Robin K., Baier J., Avigne W., Lai J., Messing J., Koch K.E., Hannah L.C. (2005). Steady-state transposon mutagenesis in inbred maize. Plant J. 44: 52-61.
42. Tan B.C.*, Joseph L.M., Deng W.T., Liu L.J., Li Q.B., Cline K., McCarty D.R. (2003). Molecular characterization of the Arabidopsis nine-cis-expoxycarotenoid dioxygenase gene family. Plant J. 35: 44-56.
43. Tan B.C.*, Cline K., McCarty D.R. (2001). Localization and targeting of VP14 epoxy-carotenoid dioxygenase to the chloroplast membrane. Plant J. 27: 373-382.
44. Tan B.C., Schwartz S., Zeevaart J.A., McCarty D.R.* (1997). Genetic control of abscisic acid synthesis in maize. Proc. Natl. Acad. Sci. USA 94: 12235-12240.
45. SCHWARTZ S.#, Tan B.C.#, Gage D.A., Zeevaart J.A., McCarty D.R.* (1997). Specific oxidative cleavage of carotenoids by VP14 of maize. Science 276: 1872-1875.
參考資料
榮譽
1998年，譚保才獲佛羅里達大學優秀博士畢業論文獎。
2022年6月28日，譚保才入選2022年度生命科學部國家杰出青年科學基金項目和國家自然科學基金創新研究群體項目專家評審組名單。
參考資料 >
譚保才.山東大學生命科學學院.2024-08-29
86人!基金委生命學部公布杰青、創新群體項目評審專家名單.百家號.2024-08-29