王雷，男，中共黨員，1976年6月出生于安徽省蕭縣，中國科學院植物研究所研究員。
簡介
1999年，東北師范大學獲學士；2002年，吉林農業大學獲碩士學位；2006年，中國科學院植物研究所獲博士學位。2006-2013年，在美國俄亥俄州立大學分子遺傳學系從事博士后研究。2010年3月-2010年9月，在韓國浦項科技大學作研究訪問學者。2013年11月到植物所工作。2014年度入選中央組織部第五批“青年”。
主要研究方向
生物鐘分子系統(Circadian molecular system)是生物體為了因應地球自轉而產生的晝夜環境周期性的變化，從而進化出的協調細胞內基因表達，及代謝網絡調控的分子系統。我們課題組以水稻和擬南芥為模式植物，解析植物生物鐘分子系統組成以及對植物生長發育的調控機理，主要包括對開花時間調控、細胞生長以及如何協同細胞內代謝網絡方面的分子機理研究。研究核心主要是圍繞植物生物鐘分子系統如何通過對環境信號的整合而實現對輸出系統的控制，以期為提高農作物品質與產量提供時間生物學方面的理論依據和遺傳資源。課題組主要研究方向為：
1）植物生物鐘分子系統的組成解析及關鍵因子的轉錄后水平調控；
2）水稻生物鐘分子系統的表觀遺傳控制分子機制；
3）生物鐘分子系統對植物發育的調控及相關分子機理。
研究論文
2021
Tian WW#, Wang RY#, Bo CP, Yu YJ, Zhang YY, Shin G, Kim W, Wang L*. 2021. SDC mediates 脫氧核糖核酸 methylation-controlled clock pace by interacting with ZTL in Arabidopsis. Nucleic Acids Research, doi: org/10.1093/nar/gkab128
2020
Wei H, Wang XL, Xu H, Wang L*.2020. Molecular basis of heading date control in rice. aBIOTECH, 1:219-232
Wei H, Wang XL, He YQ, Xu H, Wang L*. 2020. Clock component OsPRR73 positively regulates rice salt tolerance by modulating OsHKT2;1-mediated 鈉 homeostasis. The EMBO Journal, 2020.e105086
Li N#, Zhang YY#, He YQ, Wang Y, Wang L*. 2020. Pseudo Response Regulators regulate photoperiodic hypocotyl growth by repressing PIF4/5 transcription. 植物界 Physiology, 183(2): 686-699
Wang Y, He YQ, Su C, Zentella R, Sun TP, Wang L*. 2020. Nuclear localized O-fucosyltransferase SPY facilitates PRR5 proteolysis to fine-tune the pace of Arabidopsis circadian clock. Molecular 植物界, 3: 446-458
Wang Y#, Qin YM#, Li B, Zhang YY, Wang L*. 2020. Attenuated TOR signaling lengthens circadian period in Arabidopsis. Plant Signaling & Behavior, 2:e1710935
Kim TS, Wang L, Kim YJ, Somers DE*. 2020. Compensatory mutations in GI and ZTL may modulate 溫度 compensation in the circadian clock. 植物界 Physiology, 2: 1130-1141
2019
Zhang YY, Bo CP, Wang L*. 2019. Novel crosstalks between circadian clock and jasmonic acid pathway finely coordinate the tradeoff among plant growth, senescence and defense. International Journal of Molecular Sciences, 20: 5254
Li B#, Wang Y#, Zhang YY, Tian WW, Chong K, Jang JC, Wang L*. 2019. PRR5, 7 and 9 positively modulate TOR signaling-mediated root cell proliferation by repressing TANDEM 鋅 FINGER 1 in Arabidopsis. Nucleic Acids Research, 10: 5001-5015
2018
Zhang YY, Wang Y, Wei H, Li N, Tian WW, Chong K, Wang L*. 2018. Circadian evening complex represses jasmonate-induced leaf senescence in Arabidopsis. 摩爾 植物界, 11, 326-337.
Wang Y, Zhang YY, Wang L*. 2018, Cross regulatory network between circadian clock and leaf senescence is emerging in higher plants. Frontiers in Plant Science, 9: 700.
魏華, 王巖, 劉寶輝, 王雷. 2018. 植物生物鐘及其調控生長發育的研究進展. 植物學報, 53: 456-467.
2017
Cha JY, Kim J, Kim TS, Zeng QN, Wang L, Lee SY, Kim WY, Somers DE*. 2017. GIGANTEA acts as a co-chaperone with HSP90 to facilitate maturation of the client protein ZEITLUPE in the Arabidopsis circadian clock. Nat. Commun., 8: 3
2016
Wang L, Chong K. 2016. The essential role of cytokin in signaling in root apical meristem formation during somatic embryogenesis. Frontiers in 植物界 Science, doi: 10.3389/fpls.2015.01196.
2015
Jia YB, Tian HY, Li HJ, Yu QQ, Wang L, Friml J, Ding ZJ. 2015. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. Journal of Experimental 植物學, 4631-4642.
Choudhary M, Nomura Y, Wang L, Nakagami H, Somers DE. 2015. Quantitative circadian phosphoproteomic analysis of Arabidopsis reveals extensive clock control of key components in physiological, metabolic, and signaling pathways. Molecular & Cellular Proteomics, 14: 2243-2260.
2013
Wang L, Kim J and Somers D*. 2013. Transcriptional corepressor TOPLESS comlexes with pseudoresponse regulator proteins and histone deacetylase to regulate circadian transcription. Proc. Natl. Acad. Sci. USA, 110(2):761-766.
Kim Y, Lim J, Yeom M, Kim H, Kim J, Wang L, Somers D and Nam H*. 2013. ELF4 regulates GIGANTEA chromatin access through subnuclear sequestration. Cell Reports, 3:671-677.
2012
Zhang C, Xu YY, Guo SY, Zhu JY, Huan Q, Liu HH, Wang L, Luo GZ, Wang XJ and Chong K*. 2012. 動力學 of brassinosteroid response modulated by negative regulator LIC in rice. PLoS Genetics, 8(4): e1002686.
2010及以前
Wang L and Chong K*. Auxin brassinosteroids and G protein signaling. 2010.In Integrated G protein Signaling in Plants. Series of Signaling and Communication in Plants. 2010 page: 135-154 (Book chapter).
Wang L, Fujiwara S and Somers D*. 2010. PRR5 regulates phosphorylation, nuclear import and subnuclear localization of TOC1 in the Arabidopsis circadian clock. The EMBO Journal, 29(11):1903-1915.
Li D, Wang L, Wang M, Xu Y, Luo W, Liu Y, Xu Z, Li J and Chong K*. 2009. Engineering OsBAK1 gene as a molecular tool to improve rice 建筑 for high yield. 植物界 Biotechnology Journal, 7:791–806.
Wang L, Xu Y, Zhang C Ma QB, Kim J, Xu ZH and Chong K*. 2008. OsLIC, a novel CCCH-type 鋅 finger protein with transcription activation, mediates rice 建筑 via brassinosteroids signaling. PLoS One. 3(10):e3521.
Fujiwara S, Wang L, Han L, Suh SS, Salomé P, McClung R and Somers D*. 2008. Post-translational regulation of the Arabidopsis circadian clock through selective proteolysis and phosphorylation of pseudo-response regulator proteins. Journal of Biological 化學, 283(34):23073-83. (Co-first author, cover story).
Wang L, Xu YY, Li J, Powell R, Xu ZH and Chong K*. 2007. Transgenic rice plants ectopically expressing AtBAK1 are semi-dwarfed and hypersensitive to 24-epibrassinolide. Journal of 植物界 Physiology, 164 (5):655-64.
Liu KM, Wang L, XuYY, Chen N, Ma QB, Li F and Chong K*. 2007. Overexpression of OsCOIN, a putative cold inducible zinc finger protein, increased tolerance to chilling, salt and drought, and enhanced proline level in rice. 植物界, 226(4):1007-16.
Wang L, Xu YY, Ma QB, Li D, Xu ZH and Chong K*. 2006. Heterotrimeric G protein alpha subunit is involved in rice brassinosteroid response. Cell Research, 16(12):916-922.
Wang ZY*, Wang QM, Chong K, Wang FR, Wang L, Bai MY and Jia CG. 2006. The brassinosteroid signal transduction pathway. Cell Research, 16(5): 427-34.
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