趙一雷，男，浙江瑞安人，，上海交通大學教授，博士生導師。1994年畢業于中國科技大學應用化學系，獲得學士，1997年在北京大學化學系獲得碩士學位，2002年在香港科技大學獲得物理有機化學博士學位。2002年至2005年在美國加州大學洛杉磯分校（UCLA）進行博士后研究。
工作經歷
趙一雷曾在多個國際知名機構工作，包括中國化工信息中心、加州大學洛杉磯分校（UCLA）、美國國家標準技術研究所（NIST）。2005年至2009年，他在NIST擔任研究員。回國后，趙一雷在上海交通大學生命科學技術學院任教。
研究方向
趙一雷的研究方向涵蓋計算化學與分子生物信息學，具體包括蛋白質和脫氧核糖核酸的化學修飾、酶催化的分子機理等。此外，他還專注于計算生物化學、生物信息與醫學工程以及應用計算機軟件的研究。
主要成就
趙一雷在美期間曾獲得UCLA優秀博士后（2005）和美國菲利普莫里斯（PM-USA）的INEST Fellowship (2005-2007)。自2002年以來，他長期擔任美國化學會權威期刊論文評審人。
發表論文
1. Tang KB, Zhao YL, Chen ZY, Qian YT, Chao LZ, Zhang YH. (1994) “Effect of Cd Substitution on Superconductivity of Bi2222 Cuprates”,—Physica C., 232,131(1)
2. Li H, Huang CH, Zhao YL, Li TK, Bai J, Zhao XS, Xia XH.(1995): “Langmuir-Blodgett Film and Second Harmonic Generation of a Series of New Nonlinear Optical Rare 地球 Complexes”,— Solid State Communications. 94(9), 731-733.
3. Zhao YL, Gan LB, Huang CH, (1996, review) “C60 Ultro-thin Regulated Film”, 化學 in Universities, 1996, 11(4), 1-4. [Chinese: 趙一雷，甘良兵，黃春輝“C60的超薄有序膜”大學化學， 1996， 11（4），1-4.]
4. Luo CP, Huang CH, Gan LB, Zhou DJ, Xia WS, 壯族 QK, Zhao YL, Huang YY. (1996): “An Investigation of Photoelectrochemsitry of C60 and Its Derivatives of C60-四氫吡咯 by Monolayer Modified SnO2 Electrodes”J. Phys. Chem., 100(41), 16685-16689.
5. Zhang, B, Ma Y, Xu M, Wu K, Huang CH, Zhao YL, Zhuo DJ, Yin LM, Zhao XS (1997) “Planar Organic Microcavity of 香港警察沖鋒隊Chelate Film with Metal Mirrors”, Solid State Communications, 104(10), 593-596
6. Zhao YL, Gan LB, Zhou DJ, Luo CP, Huang CH, Jia GC, Wu T. (1997): “Synthesis of Proline Fullerene Derivative”, Chinese Science Bulletin, 42(16), 1360-1363. [Chinese: 趙一雷，甘良兵，周德健，駱初平，黃春輝，賈國成，武 “1, 3-偶極環加成反應合成L-脯氨酸C60衍生物”科學通報]
7. Zhou DJ, Zhao YL, Gan LB, Luo CP, Huang CH, Luo MJ, pan JQ, Wu Z (1997): “Synthesis of C60-Pyrrolidine Derivatives by 1,3-Dipolar Cycloaddition of Azomethine Ylides to C60”— Chemical Journal of Chinese Universities, 18(5), 665-670. [in Chinese: 周德健，趙一雷，甘良兵，駱初平，黃春輝，呂木堅，潘景岐，武輊 “含氮Ylide對C60的1, 3-偶極環加成反應法合成含吡咯環C60衍生物”高等學校化學學報]
8. Zhao YL, Zhou DJ, Yao GQ, Huang CH (1997): “Strong luminescent terbium(III)-pyrazolone complexes and their Langmuir-Blodgett films”, Langmuir, 13(15), 4060-4065.
9. Huang YY, Gan LB, Huang CH, Zhao YL, Zhai J, Zou YD, Tan J, Zhao XS. (1998): “Studies on the Langmuir Films of the Quinone Compounds with Long Alkyl Side Chains and Their Surface Potential”, Chemical Journal of Chinese Universities, 19, 1323-1325. [in Chinese: 黃巖誼，甘良兵，黃春輝，趙一雷，翟錦，鄒永德，譚俊，趙新生 “帶有長側鏈醌類化合物的Langmuir膜及其表面電勢”高等學校化學學報]
10. Lang AD, Zhai J, Huang CH, Gan LB, Zhao YL, Zhou DJ, Chen ZD. (1998): “Relationship between Structures and Photocurrent Generation Properties in a Series of Hemicyanine Congeners”, J. Phys. Chem. B. 102(8),1424-1429.
11. Huang YY, Zhao YL, Gan LB, Huang CH, Wu NZ. (1998): “Langmuir-Blodgett Film Formation of a Fullerene Dicarboxylic Acid Derivative C60(HOOCCHNHCHCOOH) and its Photocurrent Generation”, J. of Colloid and Interface Science, 204(2), 277-283.
12. Zhao YL, Gan LB, Zhou DJ, Huang CH, Jiang JZ, Liu W (1998): “Photocurrent Generation from a Self-Assembling Guest-Host LB Film of C60(HOOCCHNHCHCOOH) and Octopentyloxy Phthalocyanine,” Solid State Communications, 106(1), 43-48.
13. Zhao YL, Zhou DJ, Huang CH, Gan LB, Ying LM, Zhao XS, Zhang B, Ma Y, Xu M, Wu K (1998): “Langmuir-Blodgett Film of a Europium Complex and Its Application in a Silver Mirror Planar Microcavity”, Langmuir, 14(2), 417-422.
14. Wu YD.; Zhao YL (2001):“A Theoretical Study on the Origin of Cooperativity in the Formation of 310- and a-Helices”J. Am. Chem. Soc. 123(22), 5313-5319.
15. Wu, YD; Lin, JQ; Zhao, YL. (2002) “Theoretical study of b-peptide models: intrinsic preferences of helical structures.” Helvetica Chimica Acta, 85(10), 3144-3160.
16. Zhao YL; Wu YD. (2002): “A Theoretical Study on b-Sheet Models: Is the Formation of 氫 Bond Network Cooperative?” J. Am. Chem. Soc. 124(8), 1570-1571.
17. Zhao, YL; Houk, K. N.; Olson, L. P. (2004) “Mechanisms of Peroxynitrous Acid and 甲基 Peroxynitrite, ROONO (R = H, Me), Rearrangements: A Conformation-Dependent Homolytic Dissociation.”(Article) Journal of Physical Chemistry A, 108(27), 5864-5871.
18. Zhao, YL; Houk, K. N.; Rechavi, D.; Scarso, A.; Rebek, J. Jr. (2004) “Equilibrium Isotope Effects as a Probe of Nonbonding Attractions”(Communication), J. Am. Chem. Soc. 126(37), 11428-11429.
19. Zhao, YL; Bartberger, M.D.; Goto, K.; Shimada, K.; Kawashima, T; Houk, K. N. (2005) “Theoretical Evidence for Enhanced NO Dimerization in Aromatic Hosts: Implications for the Role of the Electrophile (NO)2 in Nitric Oxide 化學”(Communication), JACS, 127(22), 7964-7965.
20. Palmer L. C.; Zhao, YL; Houk, K. N. Rebek, J. Jr. (2005) “Diastereoselection of Chiral Acids in a Cylindrical Capsule”, Chem. Comm., 29, 3667-3669.
21. Zhao, YL; McCarren, P.R.; Houk, K. N.; Choi, BY; Toone, E. J. (2005) “Nitrosonium-Catalyzed Decomposition of S-Nitrosothiols in Solution: A Theoretical and Experimental Study.”(Article), J. Am. Chem. Soc. 127(31), 10917-10924.
22. Zhao, YL; Jones, W. H.; Monnat, F., Wudl, F.; Houk, K. N. (2005) “Mechanisms of the Thermal Decomposition of 聚砜: A DFT and CBS-QB3 study”, Macromolecules, 38(24); 10279-10285.
23. Zhao, YL; Houk, K. N. (2006) “Thionitroxides, RS-NH-O●: The Structure of the SNO Moiety in "S-Nitrosohemoglobin", A Possible NO Reservoir and Transporter”, J. Am. Chem. Soc. 128(5), 1422-1423.
24. Zhao, YL; Suhrada, C. P.; Jung, M. E.; Houk, K. N. (2006) “Theoretical Investigation of the Stereoselective Stepwise Cope Rearrangement of a 3-Vinylmethylenecyclobutane” J. Am. Chem. Soc. 128 (34); 11106-11113.
25. Edwards, N.; Helgeson, R.; Zhao, YL; Houk, K. N. (2006) “吡啶based Cavitands for Acid and Carboxylate Recognition”, Molecular Crystals and Liquid Crystals, 456, 175-192.
26. Zhao, YL*; Garrison, S.L.; Gonzalez, C.; Thweatt, W.D.; Marquez, M. (2007) “N-Nitrosation of Amines by 二氧化氮 and NO: a Theoretical Study”, Journal of Physical Chemistry A. 111, 2200-2205.
27. DeChancie, J.; Clemente, F. R.; Smith, A. J. T.; Gunaydin, H.; Zhao, Y.-L.; Zhang, X.; Houk, K. N. (2007) “How Similar are Enzyme Active Site Geometries Derived from Quantum Mechanical Theozymes to Crystal Structures of Enzyme-inhibitor Complexes? Implications for Enzyme 設計”, Protein Science, 16, 1851-1866.
28. Zhao, YL; Laufer, A.H.; Halpern, J.; Fahr, A. (2007) “氫 Migration and Vinylidene Pathway for Formation of 甲烷 in the 193 nm Photodissociation of Propene; CH3CH=CH2 and CD3CD=CD2”, Journal of Physical 化學 A.111, 8330-8335.
29. Wu, Y.-D.; Han, W.; Wang, D.-P.; Gao, Y.; Zhao, YL. (2008) “Theoretical Analysis of Secondary Structures of beta-Peptides”, Accounts of Chemical Research, 41, 1418－1427.
30. Penoni, A.; Palmisano, G.; Zhao, YL; Houk, K. N.; Volkman, J.; Nicholas, K. M. (2009) “On the Mechanism of Nitrosoarene-Alkyne Cycloaddition”, J. Am. Soc. Chem. 131(2), 653-661.
31. Bartalis, J.; Zhao, YL, Flora, J. W.; Paine, J. B.; Wooten, J. B. (2009) “碳Centered Radicals in Cigarette Smoke: Acyl and Alkylaminocarbonyl Radicals”, Analytical Chemistry, 81(2), 631-641.
32. Zhao, YL*; Flora, J. W.; Thweatt, W. D.; Garrison, S.L.; Gonzalez, C.; Houk, K.N.; Marquez, M. (2009) “磷化氫 Polymerization by Nitric Oxide: Experimental Characterization and Theoretical Predictions of Mechanism”, Inorganic Chemistry, 48(3), 1223-1231.
33. Zhao, YL*; Meot-Ner, M.; Gonzalez, C. (2009) “Ionic 氫 Bond Networks and Ion Solvation 1. An Efficient Monte Carlo / Quantum Mechanical Method for Structural Search and 能量 Computations: Ammonium/液態水”, J. Phys. Chem. A, 113(12), 2967-2974.
34. Philip Schulz, Christopher D. Zangmeister, Yi-Lei Zhao, Paul R. Frail, Sangameshwar R. Saudari, Carlos A. Gonzalez, Cherie R. Kagan, Matthias Wuttig, and Roger D. Van Zee J. Phys. Chem. C, 2010, 114 (48), pp 20843–20851.
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