必威电竞|足球世界杯竞猜平台

王暢
來源:互聯(lián)網(wǎng)

蘇州大學(xué)副教授,主要從事電離輻射損傷代謝、放射生物劑量估計和電離輻射防護(hù)藥物方面的研究。和他人合作在國內(nèi)外學(xué)術(shù)期刊發(fā)表多篇方向性論文。

人物經(jīng)歷

1995年考入陜西師范大學(xué)化學(xué)系,1999年畢業(yè)獲得理學(xué)學(xué)士。同年九月考入該校化學(xué)系,從事化學(xué)發(fā)光和微流控芯片的研究,于2002年獲得理學(xué)碩士學(xué)位。同年九月開始在中科院大連化學(xué)物理研究所攻讀博士學(xué)位,在導(dǎo)師許國旺研究員的指導(dǎo)下從事代謝組學(xué)研究——電噴霧質(zhì)譜和液相色譜-質(zhì)譜聯(lián)用技術(shù)的磷脂分析方法研究及其在磷脂代謝中的應(yīng)用。于2006年3月于中國科學(xué)院大連化學(xué)物理研究所獲得理學(xué)博士學(xué)位。2006年4月起至今于蘇州大學(xué)工作,從事電離輻射損傷代謝、放射生物劑量估計和電離輻射防護(hù)藥物的研究。

研究方向

電離輻射損傷代謝研究、放射生物劑量估計研究、電離輻射防護(hù)藥物研究

主要貢獻(xiàn)

已在國內(nèi)外期刊和會議上發(fā)表文章如下:

1 Chang Wang, Sigang Xie, Jun Yang, Qing Yang, Guowang Xu. Structural Identification of Human Blood Phospholipids Using Liquid Chromatography/Quadrupole-linear ion trap 質(zhì)量 Spectrometry. Anal. Chim.Acta, 2004, 525(1):1-10

2 Chang Wang, Hongwei Kong, Yufeng Guan, Jun Yang, Jianren Gu, Shengli Yang, Guowang Xu. Plasma Phospholipid Metabolic Profiling and Biomarkers of Type 2 糖尿病 Mellitus Based on High Performance Liquid Chromatography/Electrospray 質(zhì)量 Spectrometry and Multivariate Statistical Analysis. Anal. Chem., 2005,77:4108-4116

3 Chang Wang, Jun Yang, Peng Gao, Xin Lu,Guowang Xu. Identification of phospholipid structures in human blood by direct-injection quadrupole-linear ion-trap 質(zhì)量 spectrometry. Rapid Commun. Mass Spectrom. 2005, 19: 2443–2453

4 Chang Wang, Yun Yang, Jihua Nie. Plasma phospholipid metabolic profiling and biomarkers of rats following radiation exposure based on liquid chromatography–質(zhì)量 spectrometry technique. J. Biomed.Chromatogr,2009, 23: 1079-1085.

5 Lewen Jia, Chang Wang, Hongwei Kong, Jun Yang, Fanglou Li, Shen Lv, Guowang Xu. Effect of 人民軍MSHA Vaccine on Plasma Phospholipids Metabolic Profiling and the Ratio of Th2/Th1 Cells within Immune Organ of Mouse IgA Nephropathy, J. Pharm. Bioanal., 2007,4: 646-654

6 Lewen Jia, Chang Wang, Sumin Zhao, Xin Lu, Guowang Xu. Metabolomic identification of potential phospholipid biomarkers for chronic glomerulonephritis by using high performance liquid chromatography-質(zhì)量 spectrometry. J. Chromatogr. B, 2007, 860 (1) : 134-140

7 Lewen Jia, Chang Wang, Hongwei Kong , Zongwei Cai, Guowang Xu. Plasma phospholipid metabolic profiling and biomarkers of mouse IgA nephropathy,Metabolomics, 2006, 2(2),95-104

8 Qiurong Li, Li Tan, Chang Wang, Ning Li, Yousheng Li, Guowang Xu, and Jieshou Li. Polyunsaturated eicosapentaenoic acid changes lipid composition in lipid rafts. Eur. J. Nutrition, 2006, 45(3):144-151

9 Qiurong Li, Meng Wang, Li Tan, Chang Wang, Qian Shi, Ning Li, Yousheng Li, Guowang Xu, and Jieshou Li. Docosahexaenoic acid changes lipid composition and interleukin-2 捕手 signaling in membrane rafts. J. Lipid Res. 2005, 46: 1904-1913.

10 Jun Yang, Xinjie Zhao, Xiaoli Liu, Chang Wang, Peng Gao, Jiangshan Wang, Lanjuan Li, Jianren Gu, Shengli Yang, Guowang Xu. High Performance Liquid Chromatography-質(zhì)量 Spectrometry for Metabnomics: Potential Biomarkers for Acute Determination in Liver 函數(shù) of Chronic Hepatitis B. J.Proteome Res., 2006, 5:554-561.

11 王暢,謝四剛,楊軍,楊青,許國旺 液相色譜-線性離子阱質(zhì)譜法鑒定人血中磷脂乙醇胺類分子組成.色譜,2004,22(4):316-320.

12 王暢,鄭育芳,熊建輝,翁前鋒 Ca2 + 與乳清蛋白結(jié)合的親和毛細(xì)管電泳研究. 化學(xué)學(xué)報, 2004,62(3):279-282.

13 王暢,呂家根,章竹君 微透析采樣熒光法研究6-硫鳥嘌呤與蛋白結(jié)合作用。化學(xué)學(xué)報, 2002,60(9):1672-1676

14 Guowang Xu,Chang Wang. Structural Identification of Human Blood Phospholipids Using Liquid Chromatography/Quadrupole-linear ion trap 質(zhì)量 Spectrometry. The third Sino-Japanese Joint Seminar on Separation Sciences. 2004, 20-22.

15 Guowang Xu, Jun Yang, Chang Wang, Hongwei Kong, Xinjie Zhao, Kailong Yuan, Jiangshan Wang, Xin Lu,Metabonomics applications in disease biomarker discovery and safety and efficacy assessments of traditional chinese medicines based on GCX喬治十字勛章TOF MS and UPLC-Q-TOFMSn ,Ninth International Symposium on Hyphenated Techniques in Chromatography and Hyphenated Chromatographic Analyzers (HTC-9), York (United Kingdom), February 8th-10th, 2006.

16 Guowang Xu, Chang Wang, Jun Yang, Xinjie Zhao, Jiangshan Wang, Hongwei Kong, Kailong Yuan, Yuan Wang, Chenfei Ma, Xin Lu, Applications of GCxGC-TOF MS and UPLC/Q-TOF MSn in Metabonomics: Disease Biomarker Discovery and Safety Assessment and Quality Control of Traditional Chinese Medicines, 16th Annual Conference on Chromatography of Japan, Gifu, 2005.11

17 著作:參與撰寫《代謝組學(xué)——方法與應(yīng)用》,科學(xué)出版社(ISBN: 978-7-03-021528-4), 2008年,第8章:類脂和類脂組學(xué)(pp161-194)

科研項目:

脂類組學(xué)方法篩選急性輻射損傷生物劑量估計指標(biāo)(批準(zhǔn)號:31000385),國家自然科學(xué)基金,項目負(fù)責(zé)人。

氨基酸靶標(biāo)分析用于急性輻射損傷生物劑量估計的研究,江蘇省高校自然科學(xué)研究項目(批準(zhǔn)號:10KJB310012)

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