翟萬(wàn)銀,男,博士,副研究員,2002年6月畢業(yè)于華東師范大學(xué)生命科學(xué)院生物化學(xué)與分子生物學(xué)專業(yè),獲碩士學(xué)位。
個(gè)人信息
翟萬(wàn)銀,副研。
簡(jiǎn)歷
2011年6月畢業(yè)于中國(guó)科學(xué)院上海微系統(tǒng)與信息技術(shù)研究所微電子學(xué)與固體電子專業(yè),獲博士學(xué)位。2002年7月進(jìn)入中國(guó)科學(xué)院上海硅酸鹽研究所生物材料與組織工程研究中心。主要研究方向(1)生物材料的生物相容性研究和(2)心血管組織工程研究。主持完成上海市自然基金項(xiàng)目“用豬主動(dòng)脈瓣及人骨髓干細(xì)胞構(gòu)建人心臟瓣膜病”,國(guó)家863項(xiàng)目“新型納米藥物載體靶向控釋技術(shù)及其細(xì)胞生物學(xué)效應(yīng)研究”子課題;作為主要完成人完成了國(guó)家自然基金項(xiàng)目“復(fù)合天然交聯(lián)劑對(duì)動(dòng)物心臟瓣膜交聯(lián)作用的研究”、“天然交聯(lián)劑原花青素對(duì)動(dòng)物心臟瓣膜交聯(lián)作用的研究”,目前承擔(dān)國(guó)家自然基金面上項(xiàng)目“多酚對(duì)瓣膜彈性蛋白的交聯(lián)及其在原位組織工程瓣膜支架制備中的應(yīng)用研究”。
發(fā)表論文
1.Zhai W, Chang J, Lin K, Wang J, Zhao Q, Sun X. Crosslinking of decellularized porcine heart 維爾福集團(tuán) by procyanidins. Biomaterials
2. Zhai W, Chang J, Lu X. Procyanidins crosslinked heart valve matrix: Anti-calcification effect. Journal of Biomedical Materials Research Part B: Appl Biomater
3. Zhai W, Lu X, Chang J, Zhou Y, Zhang H. 槲皮素 crosslinked porcine heart 維爾福集團(tuán) matrix: mechanical property, stability, anti-calcification and cytocompatibility. Acta Biomaterialia
4. LüX, Zhai W (co-First author), Zhou Y, Zhou Y, Zhang H, Chang J. Crosslinking effect of Nordihydroguaiaretic acid (NDGA) on decellularized heart valve scaffold for tissue engineering, J. Mater Sci:Mater Med
5. Zhai W, Jia C, Zhao H, Xu Y. Procyanidins inhibit tumor angiogenesis by crosslinking extracellular matrix. Chin J Cancer Res
6. 翟萬(wàn)銀,吳蕾,賈春平,邵建波,徐元森 腫瘤微血管芯片的制備及其在通透性檢測(cè)方面的應(yīng)用. 功能材料與器件學(xué)報(bào), 2011,.
7. 翟萬(wàn)銀,周雙雯,賈春萍,徐元森. 藤黃酸抗腫瘤細(xì)胞生物學(xué)機(jī)制研究進(jìn)展. 細(xì)胞生物學(xué)學(xué)報(bào)
8. Zhai W, Jia C, Lou X, Jin Q, Zhao J, Xu Y. Enhanced antitumor activity of Irinotecan combined with gambogic acid on NSCLC. 21st IUBMB and 12st FAOBMB International Congress of Biochemistry and Molecular 生物學(xué), August 2-7, 2009, Shanghai, China. Abstract
9. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Akermanite, a silicate bioceramic, stimulates in vitro and in vivo angiogenesis European Cell and Material Journal, Under review.
10. Zhai W, He C, Wu L, Zhou Y, Guo L, Chen Y, Chen H, Chang J. Degradation of hollow mesoporous silica nanoparticles (HMSN) in human umbilical vein endothelial cells. NAOmedicine: Nanotechnology 生物學(xué) Medicine, Under review.
11. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Implications from comparative study on 硅containing ceramics and β-TCP: the key role of Si in in vitro cell proliferation, osteo-differentiation and angiogenesis. Biomaterials, Submitted.
12. Zhai W, Chang J. Procyanidins-crosslinked porcine heart valve matrix: mechanical characteristics, stability and biocompatibility. Oral
13. Zhai W, Chang J. Crosslinking-decellularized valvular ECM for bioprostheses using procyanidins. Chinese Biomaterials Congress, Chengdu, Oral
14. 何常亮, 翟萬(wàn)銀(共通訊作者),張紅霞, 常江,張紅峰,郭利民,陳航榕. 中空介孔硅球?qū)ρ軆?nèi)皮細(xì)胞的細(xì)胞毒性。華東師范大學(xué)學(xué)報(bào)(自然科學(xué)板)
15. Xie Y, Zhai W, Chen L, Chang J, Zheng X and Ding C. Preparation and in vitro evaluation of plasma-sprayed Mg2SiO4 coating on titanium alloy. Acta Biomaterialia
16. Zhang M, Zhai W, Lin K, pan H, Lu W, Chang J. Synthesis, in-vitro 羥基磷灰石 forming ability, and cytocompatibility of 鍶 silicate powders. Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials, Inpress.
17. Wu C, Chang J, Zhai W, Ni S, Wang J. Porous akermanite scaffolds for bone tissue engineering: Preparation, characterization, and in vitro studies. Journal of Biomedical Materials Research Part B: Applied Biomaterials
18. Zhao L, Chang J and Zhai W. Preparation and HL-7702 cell functionality of titania/chitosan composite scaffolds. J Mater Sci: Mater Med
19. Zhao W, Chang J, Zhai W. Self-setting properties and in vitro bioactivity of Ca3SiO5/CaSO4 1/2H2o composite cement. Journal of Biomedical Materials Research Part A
20. Wu C, Chang J, Zhai W and Ni S. A novel bioactive porous bredigite (Ca7MgSi4O16) scaffold with biomimetic apatite layer for bone tissue engineering.Journal of Materials Science: Materials in Medicine
21. Zhao L, Chang J, Zhai W. Experimental research of preparation and characterization of chito苯乙烯-丙烯腈共聚物/TiO2 composite films. Journal of Tissue Engineering and Reconstructive Sugery,
22. Du RL, Chang J, Ni SY, Zhai W, Wang JY, Characterization and in vitro bioactivity of 鋅containing bioactive glasses and glass-ceramics, J Biomater APPL
23. Ni S, Chang J, Chou L, Zhai W. Comparison of osteoblast-like cell responses to 鈣 silicate and tricalcium 磷酸鹽 ceramics in vitro. J Biomed Mater Res B
24. Xie Y, Zheng X, Ding C, Zhai W, Chang J, and Ji H. Preparation and Characterization of CaO-ZrO2-SiO2 Coating for Potential Application in Biomedicine. J Thermal Spray Technol
25. Zhao W, Chang J, Wang J, Zhai W and Wang Z. In vitro bioactivity of novel tricalcium silicate ceramics. Journal of Materials Science: Materials in Medicine
26. Wang KW, Zhu YJ, Chen XY, Zhai W, Wang Q, Chen F, Chang J and Duan Y-R. Flower-like hierarchically nanostructured hydroxyapatite hollow spheres: facile preparation and application in anticancer drug cellular delivery. Chemistry – An Asian Journal
27. Ning C, Ding D, Dai K, Zhai W and Chen L. The effect of Zr content on the microstructure, mechanical properties and cell attachment of 德州儀器35Nb–xZr alloys. Biomed. Mater
28. Chen F, Tang QL, Zhu YJ, Wang KW, Zhang ML, Zhai W, Chang J. 羥基磷灰石 nanorods/poly(vinyl pyrolidone) composite nanofibers, arrays and three-dimensional fabrics: Electrospun preparation and transformation to hydroxyapatite nanostructures. Acta Biomaterialia
29. Wanyin Zhai, Kaili Lin, Jiang Chang. Study on crosslinking of porcine heart 維爾福集團(tuán) matrix using procyanidins. The 8th Annual Meeting of Tissue Engineering Society Internation
30. 翟萬(wàn)銀,常 江,趙 強(qiáng),徐德明。組織工程心臟瓣膜病研究進(jìn)展,國(guó)外醫(yī)學(xué)。生物醫(yī)學(xué)工程學(xué)
31. 翟萬(wàn)銀,朱振勤,陳季武,王云丹,趙子寅,胡天喜。雷震子護(hù)康膠囊制劑抗氧化和對(duì)脫氧核糖核酸損傷保護(hù)作用研究,發(fā)光學(xué)報(bào)
32. 朱振勤,翟萬(wàn)銀,陳季武,夏晶,傅蓓蓓,謝萍,胡天喜。葡萄籽提取物抗氧化及對(duì)DNA保護(hù)作用研究,華東師范大學(xué)學(xué)報(bào)
33. Zhu ZQ, Zhai WY, Chen JW, Xia J, Xie P. Effects of grape seed procyanidin scavenging free radicals and protecting cultured bovine aortic cells from oxidative damage. Acta biochemica et biophysica sinica
34. Lin KL, Zhai WY, Ni SY, Chang J, Zeng Y, Qian W, Study of the mechanical property and in vitro biocompatibility of casio3 ceramics, Ceramics Inter松下電器
35. Wenyuan Zhao, Junying Wang, Wanyin Zhai, Zheng Wang, Jiang Chang. The self-setting properties and in vitro bioactivity of tricalcium silicate.Biomaterials
36. Wu CT, Chang J, Zhai WY, A novel hardystonite bioceramic: preparation and characteristics, Ceramics International
37. Gou Z, Chang J, Zhai W, Preparation and characterization of novel bioactive dicalcium silicate ceramics. J. Eur. Ceram. Soc
38. Zhao L, Chang J, Zhai W. Effect of dissolution and different crystallographic phasephases of TiO2 on hepatocyte response in vitro. Journal of Biomaterials Applications
39. Gou Z, Chang J, Zhai W, Wang JY, Study on the self-setting property and the in vitro bioactivity of b-ca(clo)2SiO4, Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials
40. Wu CT, Chang J, Wang JY, Ni SY, Zhai WY, Preparation and Characteristics of a 鈣 鎂 Silicate (Bredigite) Bioactive Ceramic. Biomaterials
專利
(1)常江,翟萬(wàn)銀. 發(fā)明名稱“具有生物活性的人工生物瓣瓣膜的制備方法”.中國(guó)專利獎(jiǎng)號(hào)
(2)常江,翟萬(wàn)銀. 發(fā)明名稱“采用槲皮素交聯(lián)制備人工生物心臟瓣膜病材料的方法”.中國(guó)專利申請(qǐng)?zhí)?/p>
(3)常江,翟萬(wàn)銀. 發(fā)明名稱“一種可再細(xì)胞化的人工生物心臟瓣膜”.中國(guó)專利申請(qǐng)?zhí)?/p>
參考資料 >
翟萬(wàn)銀.中國(guó)科學(xué)院上海硅酸鹽研究所.2012-12-10