周江寧，男，1956年10月4日出生于江蘇省南京市。現(xiàn)任中國(guó)科技大學(xué)生命科學(xué)院神經(jīng)科學(xué)與生物物理學(xué)系主任、神經(jīng)生物學(xué)教授，博士生導(dǎo)師。中國(guó)神經(jīng)科學(xué)學(xué)會(huì)常務(wù)理事、中國(guó)神經(jīng)科學(xué)學(xué)會(huì)神經(jīng)發(fā)育專業(yè)委員會(huì)主任委員。中國(guó)藥理學(xué)學(xué)會(huì)抗衰老和癡呆專業(yè)委員會(huì)副主任委員。
人物經(jīng)歷
1998年回國(guó)在安徽醫(yī)科大學(xué)第一附屬醫(yī)院工作，曾任老年醫(yī)學(xué)教授，副主任醫(yī)師，副院長(zhǎng)，安徽省老年病研究所所長(zhǎng)，中科院知識(shí)創(chuàng)新工程重要方向項(xiàng)目首席科學(xué)家，中國(guó)科學(xué)神經(jīng)科學(xué)會(huì)理事。
周江寧，1985年寧夏醫(yī)科大學(xué)碩士畢業(yè)，1996年荷蘭AMSTERDAM 大學(xué)醫(yī)學(xué)系博士畢業(yè)。1996年至1998年荷蘭皇家科學(xué)院腦研究所博士后。1998年回國(guó)在安徽醫(yī)科大學(xué)第一附屬醫(yī)院工作，曾任老年醫(yī)學(xué)教授，副主任醫(yī)師，副院長(zhǎng)，安徽省老年病研究所所長(zhǎng)，中科院知識(shí)創(chuàng)新工程重要方向項(xiàng)目首席科學(xué)家，中國(guó)科學(xué)神經(jīng)科學(xué)會(huì)理事。2001年入選中國(guó)科學(xué)院“百人計(jì)劃”。2002年建立了國(guó)內(nèi)第一家“中國(guó)人腦庫”。現(xiàn)為國(guó)家973項(xiàng)目中期評(píng)估組專家成員。承擔(dān)了國(guó)家重點(diǎn)基礎(chǔ)研究發(fā)展規(guī)劃項(xiàng)目（973）、國(guó)家高新技術(shù)領(lǐng)域規(guī)劃項(xiàng)目（863）、國(guó)家國(guó)際合作重點(diǎn)項(xiàng)目、國(guó)家中華人民共和國(guó)國(guó)家自然科學(xué)基金委員會(huì)項(xiàng)目等國(guó)家級(jí)項(xiàng)目九項(xiàng)，獲資助經(jīng)費(fèi)近800萬元。
研究獲獎(jiǎng)
主要從事神經(jīng)精神系統(tǒng)疾病的發(fā)病機(jī)制與診治基礎(chǔ)的研究。在以“自然”為代表的SCI期刊發(fā)表論文40篇。Nature 論文被評(píng)為1995年世界100項(xiàng)重大科學(xué)發(fā)現(xiàn)之一。
2000年獲安徽省科技進(jìn)步（自然科學(xué)類）一等獎(jiǎng)。
2002年國(guó)際“性別鑒定研究和教育學(xué)會(huì)”研究論文獎(jiǎng)；
國(guó)家“百千萬”工程第一、第二層次人選；
國(guó)家級(jí)有突出貢獻(xiàn)的中青年專家，教育部骨干教師，享受國(guó)務(wù)院政府特殊津貼。
研究方向
腦的性分化和相關(guān)疾病
Alzheimer 病的發(fā)病機(jī)制和診治基礎(chǔ)
抑郁癥的發(fā)病機(jī)制和診治基礎(chǔ)
1.
腦的性分化和相關(guān)疾病
2.
Alzheimer 病的發(fā)病機(jī)制和診治基礎(chǔ)
3.
抑郁癥的發(fā)病機(jī)制和診治基礎(chǔ)
近五年承擔(dān)國(guó)家科技計(jì)劃項(xiàng)目情況：
代表論著
Zhou J-N., Hofman M. A., Gooren L. J. G and Swaab D. F. A sex difference in the human brain and its relation to transsexuality . Nature. Vol.378,68-70 (1995).
Zhou J-N., Hofman M. A. and Swaab D. F.VIP neurons in the human SCN in relation to sex ,age and Alzheimer’s disease. 神經(jīng)科學(xué) of Aging. Vol.16,571-576(1995).
Zhou J-N., Hofman M. A. and Swaab D. F. No changes in the number of vasoactive intestinal 多肽定制(VIP)-expressing neurons in the suprachiasmatic nucleus of homosexual men; comparison with vasopressin-expressing neurons. Brain Research. Vol.672,285-288(1995).
Zhou J-N., Swaab D. F. Age-related changes in neuropeptidergic neurons in the human hypothalamus. in Molecular Basis of Aging. ed by Macieira-Coelho A.CRC press,Boca Raton, pp. 527-552(1995).
Zhou J-N., Hofman M. A. and Swaab D. F. Morphometric analysis of vasopressin and vasoactive intestinal 多肽定制 neurons in the human suprachiasmatic 細(xì)胞核, influence of 微波 treatment. Brain Research. 742,334-338(1996).
Zhou J-N., Hofman M. A. and Swaab D. F. Alteration in the human hypothalamus start in middle age but are more severe in Alzheimer's Disease. Neurobiology of Aging. 19, S309(1998).
Zhou J-N. and Swaab D. F. Activation and degeneration during aging, A morphometric study of the human hypothalamus. In Histology of the hypothalamic-pituitary axis. Microscopy Research and Techniques. 44, 36-48(1999).
Zhou J-N., Hu X-Y., Liu R-Y., Qin S. Ostrogen receptor containing neurons decrease in the hippocampus of Alzheimer patienTS 神經(jīng)科學(xué) Aging. 21, s264(2000).
Zhou J-N., Riemersma R. F, Witte Hoogendijk. J. G., Swaab D. F. Alterations in Arginine Vasopressin Neurons in the Suprachiasmatic 細(xì)胞核 in Depression. Arch Gen Psychlatry. VOL.58,July 2001;58,655-662(2001).
Zhou J-N., Liu R-Y., Van Heerikhuize J., Hofman M. A. and Swaab D. F. Alterations in the circadian rhythm of salivary melatonin begin during middle-age. J. Pineal Res. 34,11-16(2003).
周江寧 (2001) 衰老和阿爾茲海默癥中晝夜節(jié)律調(diào)節(jié)系統(tǒng)的改變, 復(fù)旦大學(xué)神經(jīng)科學(xué)講座, NO.255。
周江寧，劉榮玉.。 (2000) 老年性癡呆的非藥物治療 老年性癡呆的治療和護(hù)理（盛樹立主編）, pp. 158-175，科學(xué)技術(shù)文獻(xiàn)出版社。
周江寧（2002）雌激素與Alzheimer Disease.。神經(jīng)科學(xué)進(jìn)展（科學(xué)出版社）pp,315-318。
周江寧（2001）前額葉皮質(zhì)與下丘腦在抑郁癥發(fā)病中的作用。安徽醫(yī)科大學(xué)學(xué)報(bào)。Vol.36 No.4,247-250。
Liu R-Y, Zhou J-N., Hoogendijk W. J. G., Van Heerikhuize J., Kamphorst W, Unmehopa U. A., Hofman M. A., and Swaab D. F. Decreased vasopressin mRNA expression in the suprachiasmatic 細(xì)胞核 in Alzheimer's disease. J. Neuropath Exp Neurol. 59（4）,314-322(2000).
Liu R-Y., Zhou J-N. Alteration of vasopressin mRNA expression in the suprachiasmatic nucleus of the patients with Alzheimer’s disease. 神經(jīng)科學(xué) Aging. 21, s54(2000).
Liu R-Y, Zhou J-N, Van Heerikhuize J, Hofman M. A and Swaab D. F. Decreased melationin levels in postmortem cerebrospinal fluid in elation to aging, Alzheimer’s disease and ApoE-ε4/4 基因型 J. Clin Endocr&Metab. 84,323-327(1999).
Liu R-Y, Zhou J-N, Kamphorst W, Hofman M.A, Swaab D.F The first appearance of neurofibrillary tangles and plaques in the temporal cortex of aged controls is accompanied by decreased cerebrospinal fluid melatonin levels. 神經(jīng)科學(xué) of aging. Vol.23, Iss1, pp,1397- (2002)
Liu R-Y, Zhou J-N (2001). Biological Rhytm disorder, In aging and Alzheimer’s disease. Neuroendocrinologie des demences. Pp,11-30..
劉榮玉, 周江寧。糖皮質(zhì)激素對(duì)人視交叉上核加壓素表達(dá)的影響。中國(guó)藥理學(xué)通報(bào)。16（3）,286-289 (2000)。
劉榮玉, 周江寧。腦脊液松果腺體素晝夜和季節(jié)節(jié)律在衰老和阿爾茲海默癥中的改變。中華老年醫(yī)學(xué)雜志。19（4）,258-261(2000)。
劉榮玉, 周江寧。人視交叉上核加壓素基因表達(dá)的晝夜節(jié)律改變。安徽醫(yī)科大學(xué)學(xué)報(bào)35（2）,88-90(2000)。
Swaab D. F., Zhou J-N., Ehlhart T. and Hofman M. A. Development of vasoactive intestinal polypeptide neurons in the human suprachiasmatic 細(xì)胞核 in relation to birth and sex. Development of Brain Research. Vol.79,249-259(1994).
Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Gender and sexual orientation-related differences in the human hypothalamus. in Sex differentiation clinical and biological aspect(ed.Hughes). Frontiers in Endocrinology 20, Cambridge, 135-152(1996).
Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Sexual differentiation of the human hypothalamus, differences according to sex, sexual orientation, and transsexuality in Sexual Orientation Toward Biological Understanding. (ed by Ellis L., Praeger, Westport) pp.129-150(1997).
Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Sexual differentiation of the human brain. Biomedical Reviews. 7, 17-32(1997).
Swaab D. F., Hofman M. A., Van Smeren E. J. W. and Zhou J-N. (1993). Development and aging of the biological clock. In De Biologische klok praktische toepassingen in klinjek en huisartspraktijk. (ed. Rietved W. J and Kerkhof G. A Leiden 1993) pp. 9-23.
Swaab D. F., Hofman M.A., Mirmiran M., Van Someren E. J. W., and Zhou J-N. The human suprachiasmatic mucleus (SCN) in a periodic environment. New functional aspect of the suprachiasmatic 細(xì)胞核 pp. 232-336(1994).
Swaab D. F., Slob A. K., Houtsmuller E. J., Brand T. and Zhou J-N. Increased number of vasopressin neurons in the suprachiasmatic nucleus (SCN) of ‘bisexual’ adult male rats fllowing perinatal treatment with the aromataes blocker ATD. Dev. Brain Research. Vol.85,273-279(1995).
Swaab D.F, Fliers E, Hoogendijk W.J.G, Veltman D.J, Zhou J-N. Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression. Progress in brain research.Vol.126, pp,369-396(2001)
Swaab D.F., VanSomeren E.J.W., Zhou J-N, Hofman M.A. (1996) Biological rhythms in the human life cycle and their relationship to functional changes in the suprachiasmatic 細(xì)胞核 Hypothalamic integration of circadian rhythms. Vol.111, pp,349-368.
Hofman M.A., Zhou J-N, Swaab D.F. No evidence for a diurnal vasoactive intestinal 多肽定制(VIP) rhythm in human suprachiasmatic 細(xì)胞核 Brain Research. Vol.722,78-82(1996).
Hofman M.A., Zhou J-N, Swaab D.F. Suprachiasmatic nucleus of the human brain, An immunocytochemical and morphometric analysis. Anatomical Record. Vol.244,552-562(1996).
Hoogendijk W. J. G., Van Someren, E. J. W., Mirmiran M., Hofman M. A., Lucassen P. L., Zhou J-N and Swaab D. F. Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer’s disease. International Psychogeriatrics. Vol.8,245-252 (1996).
Kruijver F. P. M., Zhou J-N, Pool C. W., Hofman M. A., Gooren L. J. G., Swaab D. F. Male-to-female transsexuals have female neuron numbers in a limbic neurocleus. J Clin Endocr&Metab. 85,2034-2041 (2000).
Wang Q-S, Zhou J-N, Xu T-L, Li L-S A phospholipase C inhibitor, phenylmethylsulfonyl fluoride, ameliorates ischemic injury to brain mitochondria in rats. Acta Pharmacol Sin, Mar, 22（3）,249-252 (2001).
Wang Q-S, Zhou J-N. Retrieval and encoding of epsodic memory in normal aging and patients with mild cognitive inpairment. Brain Research. 924,113-115(2002).
Wang Q-S, Tian L, Huang Y-L, Qin S, He L-Q, Zhou J-N. Olfactory identification and apolipoprotein Eε4 allele in mild cognitive impairment. Brain Research. 951,77-81(2002).
Wang Q-S, Qin S, Zhou J-N. Olfactory identification and apolipoprotein E epsilon-4 allele in mild cognitive impairment. 神經(jīng)科學(xué) of aging. Vol.23, Iss1, pp,635- (2002)
汪青松，許浩，秦松，趙卉，吳穎慧，黃永璐，周江寧。輕度認(rèn)知損害患者情節(jié)記憶的編碼和提取。中國(guó)神經(jīng)科學(xué)雜志。Vol.18 No.1,451-463（2002）。
Hu X-Y, Zhang H-Y, Qin S, Xu H, Swaab D. F., Zhou J-N. (Increased p75NTR expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients. 神經(jīng)科學(xué) of aging. Vol,23, Iss1, pp,997-.2002).
Hu X-Y, Zhou J-N, Swaab D.F Decreeased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphorylated tau in Alzheimer patients. 神經(jīng)科學(xué) of aging. Vol.23, Iss1, pp,1808- (2002).
Huang Y-L, Liu R-Y, Wang Q-S, Van Someren E.J.W., Xu H, Zhou J-N. Age-associated difference in circadian sleep-wake and rest-activity rhythms. Physiology&Behavior. 76, 597-603(2002).
黃永璐，汪青松，吳穎慧，周江寧。晝夜靜息-活動(dòng)、睡眠-覺醒節(jié)律的年齡相關(guān)性變化。安徽醫(yī)科大學(xué)學(xué)報(bào)。Vol.37 No.1,44-46（2002）。
Xu H, Hu X-Y, Wu L, Zhou J-N.(2002) Neurotensin expressing neurons developed earlier than vasoactive intestinal 多肽定制 and vasopressin expressing neurons in the human suprachiasmatic 細(xì)胞核 Neuroscience Letters.
許浩，胡祥友，秦松，周江寧。阿爾茲海默癥腦海馬凋亡神經(jīng)元發(fā)生率增高。中國(guó)神經(jīng)科學(xué)雜志。Vol.18 No.1,462-465（2002）.
Wang K, Hoosain R, Li X-S, Zhou J-N, Wang C-Q, Fu X-M, Yue X-M. Impaired recognition of fear in a Chinese man with bilateral cingulated and unilateral amygdala damage. Cognitive neuropsychology. Vol.19,pp,641-652(2002).
Bao A-M, Zhou J-N, Liu R-Y, Wang Y-L, Cao Y-X, Chu X-H Circadian rhythm of free estrogen during menstrual cycle and its periodic regression analysis. 神經(jīng)科學(xué) of aging. Vol.23, Iss 1, pp,640-(2002)
陳貴海，周江寧。神經(jīng)遞質(zhì)認(rèn)識(shí)過程的哲學(xué)思考。醫(yī)學(xué)與哲學(xué)。Vol.23 No.3,9-11（2002）。
參考資料 >
周江寧簡(jiǎn)歷_中科大神經(jīng)生物學(xué)與生物物理學(xué)系主任周江寧受邀參會(huì)演講_活動(dòng)家.活動(dòng)家.2022-02-08