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王育才
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王育才,男,中國科學(xué)技術(shù)大學(xué)教授、博士生導(dǎo)師,畢業(yè)于該校并獲得研究生學(xué)歷。他是國家杰出青年基金獲得者。

人物經(jīng)歷

教育經(jīng)歷

工作經(jīng)歷

2011年1月起先后于圣路易斯華盛頓大學(xué)生物醫(yī)學(xué)工程系、佐治亞理工學(xué)院生物醫(yī)學(xué)工程系及芝加哥大學(xué)James Franck研究所從事博士后研究。

2015年回到中國科學(xué)技術(shù)大學(xué)生命科學(xué)學(xué)院任教。

多年來一直從事納米材料在癌癥治療及成像領(lǐng)域的研究,在Nat Mater、Nat Commun、PNAS、NanoLetters、ACS Nano國際學(xué)術(shù)期刊發(fā)表研究論文70余篇,引用次數(shù)超過5000次,H-index?為39。

主要成就

科研成就

主要研究

1.可降解生物材料

2.納米藥物用于癌癥診療。

論文

在國際學(xué)術(shù)期刊發(fā)表研究論文50余篇,引用次數(shù)超過2600次,還為Advanced Functional Materials及Macromolecular Bioscience撰寫邀請(qǐng)綜述,并為Nature Materials撰寫論文評(píng)論。

H. X. Wang, Z. Q. 左姓, J. Z. Du, Y. C. Wang*, R. Sun, Z. T. Cao, X. D. Ye, J. L. Wang, K. W. Leong*, J. Wang*. Surface Charge critically affects tumor penetration and therapeutic efficacy of cancer nanomedicines. Nano Today, 2016, accepted

Z. T. Cao, Z. Y. Chen, C. Y. Sun, H. J. Li, H. X. Wang, Q. Q. 成姓, Z. Q. 左姓, J. L. Wang, Y. Z. Liu, Y. C. Wang*, J. Wang*. Overcoming tumor resistance to cisplatin by cationic lipid-assisted prodrug nanoparticles. Biomaterials, 2016, accepted, 2016, DOI:10.1016/j.biomaterials.2016.04.001

Z. Q. 左姓, K. G. Chen, X. Y. Yu, G. Zhao, S. Shen, Z. T. Cao, Y. L. Luo, Y. C. Wang, J. Wang*. Promoting Tumor Penetration of Nanoparticles for Cancer Stem Cell Therapy by TGF-β Signaling Pathway Inhibition. Biomaterials, 2016, 82, 48-59

Y. C. Ma, J. X. Wang, W. Tao*, C. Y. Sun, Y. C. Wang*, D. D. Li, F. Fan, H. S. Qian, X. Z. Yang*. Redox-Responsive Polyphosphoester-Based Micellar Nanomedicines for Overriding Chemoresistance in Breast Cancer Cells. ACS Applied Materials & Interfaces,2015, 7, 26315-26325

Z. Luo#, Y. Jiang#, B. Myers, D. Isheim, J. Wu, J. Zimmerman, Z. Wang, Q. Li, Y. C. Wang, X. Chen, V. P. Dravid, D. N. Seidman, B. Tian*. Atomic Gold–Enabled Three-Dimensional Lithography for Mesostructures. , 2015, 348, 1451-1455.

J. Zimmerman, M. Murray, Y. C. Wang, J. Jumper, J. Austin, B. Tian*, Free-Standing Kinked Silicon Nanowires for Probing Inter-and Intracellular Force 動(dòng)力學(xué) Nano Letters, 2015, 15, 5492-5498.

Y. C. Wang#, M. S. Shim#, N. S. Levinson, H-W. Sung, Y. Xia*.Stimuli-Responsive Materials for Controlled Release of Theranostic Agents. Advanced Functional Materials, 2014, 24, 4206-4220

K. C. L. 黑色#, Y. C. Wang#, H. P. Luehmann, X. Cai, W. X. Xing, B. Pang, Y. F. Zhao, C. S. Cutler, L. V. Wang, Y. Liu*,Y. Xia*. Radioactive 198Au-Doped Nanostructures with Different Shapes forin vivoAnalyses of Their Biodistribution, Tumor Uptake, and Intratumoral Distribution. ACS Nano, 2014, 8, 4385-4394

T. M. Sun#, Y. C. Wang#, F. Wang, J. Z. Du, C. Q. Mao, C. Y. Sun, R. Z. Tang, Y. Liu, J. Zhu, Y. H. Zhu, X. Z. Yang, J. Wang*. Cancer Stem 細(xì)胞 Therapy Using Doxorubicin Conjugated to Gold Nanoparticles via Hydrazone Bonds. Biomaterials,2014, 35, 836-845.

T. M. Sun, Y. Wang, Y. C. Wang, Y. Xia*. Using SV119-Gold Nanocage Conjugates to Eradicate Cancer Stem Cells through a 組合 of Photothermal and Chemo Therapies. Advanced Healthcare Materials, 2014, 3, 1283-1291

Y. C. Wang#, Y. Liu#, H. Luehamn, X. Xia, D. Wan, C. Cutler, Y. Xia*. Radioluminescent Gold Nanocages with Controlled Radioactivity for Real-時(shí)間 in vivo Imaging. Nano Letters, 2013, 13, 581-585.

Y. C. Wang#,K. C. L. 黑色#, H. Luehmann, W. Li, Y. Zhang, X. Cai, D. Wan, S. Liu, M. Li, P. Kim, Z. Li, L. V. Wang, Y. Liu*, Y. Xia*. Comparison Study of Gold Nanohexapods, Nanorods, and Nanocages for Photothermal Cancer Treatment. ACS Nano,2013, 7, 2068-2077.

D. Wan, X. Xia, Y. C. Wang, Y. Xia*. Robust Synthesis of Gold Cubic Nanoframes through a 組合 of Galvanic Replacement, Gold Deposition, and Silver Dealloying. Small,2013, 9, 3111-7

K. J. Chen, H. F. Liang, H. L. Chen; Y. C. Wang; P. Y. 成姓; Liu, H. L. Liu; Y. Xia*, H. W. Sung*.A Thermoresponsive Bubble-Generating Liposomal System for Triggering Localized Extracellular Drug Delivery. ACS Nano,2013, 7, 438-446.

Y. Zhang, Y. Wang, L. Wang, Y. C.Wang, X. Cai, C. Zhang, L. V. Wang, Y. Xia*. Labeling Human Mesenchymal Stem Cells with Au Nanocages for in vitroand in vivoTracking by Two-Photon Microscopy and Photoacoustic Microscopy. Theranostics, 2013, 3, 532-543.

W. Li#, F. Wang#, Z. Liu, Y. C. Wang, J. Wang*, F. Sun*. Gold Nanoparticles Elevate 等離子體 Testosterone Levels in Male Mice without Affecting Fertility. Small, 2013, 9, 1708-1714.

W. Li#, C. Sun#, F. Wang, Y. C. Wang, Y. Zhai, M. Liang, W. Liu, Z. Liu, J. Wang*, F. Sun*. Achieving a New Controllable Male Contraception by the Photothermal Effect of Gold Nanorods. Nano Letters, 2013, 13, 2477-2484.

H. X. Wang#, M. H. Xiong#, Y. C. Wang, J. Zhu. J. Wang*. N-Acetylgalactosamine Functionalized Mixed Micellar Nanoparticles for Targeted Delivery of si核糖核酸 to Liver. Journal of Controlled Release, 2013, 166, 106-114.

J. Wu#, T. M. Sun#, X. Z. Yang*, J. Zhu, X. J Du, Y. D. Yao, M. H. Xiong, H. X. Wang, Y. C Wang, J. Wang*. Enhanced Drug Delivery to Hepatocellular Carcinoma with a Galactosylated Core–Shell Polyphosphoester Nanogel. Biomaterial Sciences, 2013, 1, 1143-1150.

Y. C. Wang#, Y. Liu#,*, H. Luehmann, X. Xia, P. Brown, C. Jarreau, M. Welch, Y. Xia*. Evaluating the Pharmacokinetics and In VivoCancer Targeting Capability of Au Nanocages by Positron Emission Tomography Imaging. ACS Nano,2012, 6, 小行星58805888.

Y. C. Wang, Y. Wang, F. Zhou, P. Kim, Y. Xia*. Protein-Protected Au Clusters as a New Class of Nanoscale Biosensor for Label-Free 熒光 Detection of Proteases. Small, 2012, 8, 3769-3773.

S. Xie, M. Jin, J. Tao, Y. C. Wang, Z. Xie, Y. Zhu, Y. Xia*. Synthesis and Characterization of Pd@MxCu1-x (M=Au, Pd, and Pt) Nanocages with Porous Walls and a Yolk-Shell Structure through Galvanic Replacement Reactions. 化學(xué) of Materials, 2012, 18, 14974–14980.

X. Xia, M. X. Yang, Y. C. Wang, Y. Zheng, Q. Li, J. 成姓*, Y. Xia*. Quantifying the Coverage 密度 of Poly(乙烯 glycol) Chains on the surface of Gold Nanostructures. ACS Nano,2012, 6, 512–522.

X. Z. Yang, S. Dou, Y. C. Wang, H. Y. Long, M. H. Xiong, C. Q. Mao, Y. D. Yao. J. Wang*. Single-Step Assembly of Cationic Lipid-Polymer Hybrid Nanoparticles for Systemic Delivery of siRNA. ACS Nano, 2012, 6, 4955–4965.

M. H. Xiong#, Y. Bao#, X. Z. Yang, Y. C. Wang, B. Sun*, J. Wang*. Lipase-Sensitive Polymeric Triple-Layered Nanogel for "On-Demand" Drug Delivery.Journal of the American Chemical Society2012, 134, 4355–4362.

Y. C. Wang, J. Xu, X. Xia, M. Yang, S. Vangverarong, J. Chen, R. H. Mach, Y. Xia*. SV119-Gold Nanocage Conjugates: a New Platform for Targeting Cancer Cells viasigma2 Receptors. , 2011, 4, 421424.

Y. C. Wang, P. Brown, Y. Xia*. Swarming to the Target. Nature Materials, 2011, 10, 482–483(News & Views)

Y. C. Wang#,F. Wang#, T. M. Sun, J. Wang*. Redox-Responsive Nanoparticles from the Single Disulfide Bond-Bridged Block Copolymer as Drug Carriers for Overcoming Multi-Drug Resistance in Cancer Cells. Bioconjugate 化學(xué), 2011, 22, 1939–1945

F. Wang#, Y. C. Wang#, S. Dou, M. H. Xiong, T. M. Sun, J. Wang*. Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells. , 2011, 5, 3679–3692

Y. C. Wang,Y. Y. Yuan, F. Wang, J. Wang*,Syntheses and Characterization of Block Copolymers of Poly(aliphatic ester) with Clickable Polyphosphoester. , 2011, 49, 487–494.

獲得榮譽(yù)

參考資料 >

王育才教授.中國科學(xué)技術(shù)大學(xué).2022-01-12

今年“杰青”名單出爐!共300人,來自124家單位_科技湃_澎湃新聞-The Paper.澎湃新聞.2020-08-12

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