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戈鈞
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戈鈞,博士,特別研究員,博士生導師,清華大學化學工程系生物化工研究所工業生物催化教育部重點實驗室。

研究方向:酶固定化/化學修飾,工業生物催化,生物傳感器。

2018年5月,戈鈞入選“長江學者獎勵計劃”青年學者。

人物介紹

戈鈞,中國“80后”青年科學家,畢業于清華大學,美國斯坦福大學博士后,被《麻省理工學院科技評論》雜志評選的2015年度全球杰出青年創新人物(TR35)。

教育經歷

2000年-2004年,清華大學,化工系,高分子材料專業,學士

2004年-2009年,清華大學,化工系,生物化工專業,博士

2009年-2012年,斯坦福大學,化學系,博士后

2012年1月-2012年12月,清華大學,化工系,講師

2012年12月-2016年8月,清華大學,化工系,副教授,博士生導師

2016年9月至今,清華大學,化工系,特別研究員,博士生導師

研究方向

酶固定化/化學修飾,工業生物催化,生物傳感器

從事酶固定化方法及其在工業生物催化和生物傳感器領域的應用研究。作為項目負責人主持國家自然科學基金優秀青年基金、國家重點研發計劃納米科技重點專項青年科學家項目、生物與醫藥領域863計劃青年科學家專題等項目。研究工作發表論文40余篇,部分論文發表在Nature Nanotechnology, Nano Letters, ACS Nano, ACS Catalysis等期刊。2015年入選麻省理工學院 Technology Review評選的World 35 Innovators Under 35。

代表論文

Zhang, C.; Wang, X.; Hou, M.; Li, X.; Wu, X.; Ge, J.* Immobilization on metal-organic framework engenders high sensitivity for enzymatic electrochemical detection. ACS Applied Materials & Interfaces 2017, DOI: 10.1021/acsami.7b02803

Wu, X.; Ou, G.; Yang, C.; Ge, J.*, Wu, H.* Enhanced enzymatic reactions by solar-to-thermal conversion nanoparticles. Chemical Communications 2017, DOI: 10.1039/C7CC01522D

Li, Z.; Ding, Y.; Li, S.; Jiang, Y.*; Liu, Z.; Ge, J.* Highly active, stable and self-antimicrobial enzyme catalysts prepared by biomimetic mineralization of copper hydroxysulfate. Nanoscale 2016, 8, 17440-17445.

Wu, X.; Yang, C.; Ge, J.*; Liu, Z. Polydopamine tethered enzyme/metal-organic framework composites with high stability and reusability. Nanoscale 2015, 7, 18883-18886. (Featured on the Cover)

Wu, X.; Hou, M.; Ge, J.* Metal-organic frameworks and inorganic nanoflowers: a type of emerging inorganic crystal nanocarriers for enzyme immobilization. Catalysis Science & Technology 2015, 5, 5077-5085. (Invited Review)

Zhang, Y.; Ge, J.*; Liu, Z.* Enhanced activity of immobilized or chemically modified enzymes. ACS Catalysis 2015, 5, 4503-4513. (Invited Review)

Wu, X.; Ge, J.*; Yang C.; Hou, M.; Liu, Z. Facile synthesis of multiple enzyme-containing metal-organic frameworks in a biomolecule-friendly environment. Chemical Communications 2015, 51, 13408-13411.

Wu, X.; Ge, J.*; Zhu, J.; Zhang, Y.; Yong, Y.; Liu, Z.* A general method for synthesizing enzyme-polymer conjugates in reverse emulsions using Pluronic as a reactive surfactant. Chemical Communications 2015, 51, 9674-9677.

Lyu, F.; Zhang, Y.; Zare, R. N.; Ge, J.*; Liu, Z.* One-pot synthesis of protein-embedded metal-organic frameworks with enhanced biological activities. Nano Letters 2014, 14, 5761-5765.

Li, Z.; Zhang, Y.; Su, Y.; Ouyang, P.; Ge, J.*; Liu, Z.* Spatial co-localization of multi-enzymes by inorganic nanocrystal-protein complexes. Chemical Communications 2014, 50, 12465-12468.

Zhang, Y.; Lyu, F.; Ge, J.*; Liu, Z.* Ink-jet printing an optimal multi-enzyme system. Chemical Communications 2014, 50, 12919-12922.

Zhang, Y.; Chen, Q.; Ge, J.*; Liu, Z.* Controlled display of enzyme activity with a stretchable hydrogel. Chemical Communications 2013, 49, 9815-9817.

Zhu, J.; Zhang, Y.; Lu, D.; Zare, R. N.; Ge, J.*; Liu, Z.* 溫度responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media. Chemical Communications 2013, 49, 6090-6092.

Wang, R.; Zhang, Y.; Huang, J.; Lu, D.; Ge, J.*; Liu, Z.* Substrate imprinted lipase nanogel for one-step synthesis of 氯霉素 palmitate. Green 化學 2013, 15, 11551158.

Ge, J.; Lei, J.; Zare, R. N.* Protein-inorganic hybrid nanoflowers. Nature Nanotechnology 2012, 7, 428-432. (Featured on the Cover, Highlighted by Science, Nature Nanotechnology, and The Scientist)

Ge, J.; Neofytou, E.; Lei, J.; Beygui, R. E.; Zare, R. N.* Protein-polymer hybrid nanoparticles for drug delivery. Small 2012, 8, 3573-3578.

Ge, J.; Neofytou, E.; Cahill, III, T. J.; Beygui, R. E.; Zare, R. N.* Drug release from electric-field-responsive nanoparticles. ACS Nano 2012, 6, 227-233. (Highlighted by Chemical&Engineering News, ACS Nano, Nanomedicine)

Ge, J.; Lei, J. D.; Zare, R. N.* Bovine serum albumin-poly(methyl methacrylate) nanoparticles: an Example of frustrated phase separation. Nano Letters 2011, 11, 2551-2554. (Highlighted by Science)

Ge, J.; Jacobson, G. B.; Lobovkina, T.; Holmberg, K.; Zare, R. N.* Sustained release of nucleic acids from polymeric nanoparticles using microemulsion precipitation in supercritical carbon dioxide. Chemical Communications 2010, 46, 9034-9036.

Ge, J.; Lu, D.; Wang, J.; Liu, Z.* Lipase nanogel catalyzed transesterification in anhydrous dimethyl sulfoxide. Biomacromolecules 2009, 10, 1612-1618.

Ge, J.; Lu, D.; Wang, J.; Yan, M.; Lu, Y.*; Liu, Z.* Molecular fundamentals of enzyme nanogels. Journal of Physical Chemistry B 2008, 112, 14319-14324.

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