掌中彩,LH雷火官网,启航彩

來源：互聯網

焦寧，男，漢族，出生于山東省，現任北京大學藥學院教授、博士生導師、長江學者獎勵計劃特聘教授。他的研究領域包括綠色化學、地球豐產過渡金屬催化以及基于內源性物質進行成都先導發現的綠色方法。焦寧教授致力于尋找生物活性分子合成新途徑和新方法，利用簡單原料和高效的合成方法為先導藥物發現和構效關系研究服務。他曾在山東大學獲得學士，1999年—2004年，在上海有機化學研究所就讀并獲得有機化學博士學位（導師為麻生明教授）。焦寧教授曾獲得國家杰出青年科學基金，并于2021年9月榮獲第三屆“科學探索獎”。

個人經歷

教育經歷

工作經歷

2012-至今天然藥物及仿生藥物國家重點實驗室副主任。

2010-至今教授，北京大學藥學院，課題組長。

2007-2010副教授，北京大學藥學院，課題組長。

2004-2006，獲得洪堡獎學金，在德國馬普煤炭研究所從事化學生物學博士后研究，導師為曼弗雷德·雷茨（Manfred T. Reetz）教授。

主要成就

科研成就

研究領域

1）綠色化學：氧氣氧化與活化，氧合反應（Oxygenation Reactions），氮合反應（Nitrogenation Reactions）。

2）地球豐產過渡金屬催化。

3）基于內源性物質進行成都先導發現，通過可控自由基反應、惰性鍵活化、串聯催化等過程尋求生物活性分子合成新途徑、新方法，利用簡單原料以簡潔、高效的合成方法為先導藥物發現及構效關系研究服務。

論文

1. Xiaoqiang Huang, Xinyao Li, Miancheng Zou, Song Song, Conghui Tang, Yizhi Yuan, andNing Jiao*, From Ketones to Esters by a Cu-Catalyzed Highly Selective C(CO)-C(alkyl) Bond Cleavage: Aerobic Oxidation and Oxygenation with Air,J. Am. Chem. Soc.2014,136, 14858-14865.

2. Feng Chen, Xiaoqiang Huang, Xinyao Li, Tao Shen, Miancheng Zou, andNing Jiao*, Dehydrogenative N-Incorporation: A Direct Approach to 喹喔啉 N-Oxides under Mild Conditions,Angew. Chem. Int. Ed.2014, 53,10495-10499.

3. Conghui Tang andNing Jiao*, 銅Catalyzed Aerobic Oxidative C?C bond Cleavage for C?N Bond Formation: From Ketones to Amides,Angew. Chem. Int. Ed.2014,53,6528-6532. (Hot Paper).

4. Yu-Feng Liang andNing Jiao*,Transition-Metal Free Highly Efficient C-H Hydroxylation of Carbonyls with Molecular 氧 Under Mild Conditions,Angew. Chem. Int. Ed.2014,53, 548.

5. Chun Zhang, Peng Feng andNing Jiao*, 銅Catalyzed 酯化反應 Reaction via Aerobic Oxygenation and C-C Bond Cleavage: An Approach toα-Ketoesters,J. Am.Chem. Soc.2013,135, 15257–15262.

6. Teng Wang andNing Jiao*, TEMPO-catalyzed Aerobic Oxygenation and Nitrogenation of Olefins via C=C Double Bond Cleavage,J. Am. Chem. Soc.2013,135, 11692-11695.

7. Yijin Su, Xiang Sun, Guolin Wu, andNing Jiao*, catcontrolled Highly Selective 耦合 and Oxygenation of Olefins: A Direct Approach to Alcohols, Ketones and Diketones,Angew. Chem. Int. Ed.2013,52, 9808-9812 (10.1021/anie.201303917).

8. Chong Qin, Peng Feng, Yang Ou,Tao Shen, Teng Wang andNing Jiao*,Highly Selective Csp-Csp Bond Cleavage:The Nitrogenation of Alkynes to Amides,Angew. Chem. Int. Ed.2013,52, 7850-7854. (Hot Paper).

9. Tao Shen, Teng Wang, Chong Qin, andNing Jiao*, Ag-catalyzed Nitrogenation of Alkynes: A Direct Approach to Nitriles via C-C Triple Bond Cleavage,Angew. Chem. Int. Ed.2013,52, 6677-6680. (Hot Paper) (Highlighted bySynfact(2013, 9(9), 0949).

10. Yuepeng Yan, Peng Feng, Qing-Zhong Zheng,Yu-FengLiang,Jingfen Lu, andNing Jiao*, PdCl2and NHPI Cocatalyzed Csp-H HydroxylationviaDioxygen Activation,Angew. Chem. Int. Ed.2013,52, 5827-5831.

11. Conghui Tang andNing Jiao*, 銅catalyzed C-H Azidation of Anilines under Mild Conditions,J. Am. Chem. Soc.2012,134, 18924-18927.(Highlighted bySynform(2013, 02, A21) andSynfact(2013,9(2), 0207), Highlighted byAngew. Chem. Int. Ed. 10.1002/anie.201302015)

12. Xejun Xu, Chun Zhang, (These two authors contributed equally to this work) andNing Jiao*, 銅mediated Aerobic Oxidative Dehydrogenative Annulation and Oxygenation of Aldehydes and Amines for Oxazoles via C-H Functionalization and Dioxygen Activation,Angew. Chem. Int. Ed.2012,51, 11367–11370(Hot Paper).

13. Teng Wang, Wang Zhou, Hang Yin, Jun-An Ma, andNing Jiao*, Iron-Facilitated Oxidative Dehydrogenative C-O Bond Formation via Propargyl Csp3–H FunctionalizationAngew. Chem. Int. Ed.2012,51, 10823-10826.

14. Chong Qin, Tao Shen, Conghui Tang, andNing Jiao*, 氯化亞鐵promoted Unactivated C-C Bond Cleavage of Alkylarenes and Polystyrene: Direct Synthesis of Versatile Arylamines,Angew. Chem. Int. Ed.2012,51, 6971-6975(Hot Paper).

15. Shengtao Ding, andNing Jiao*, N,N-Dimethylformamide: A Multipurpose Building Block,Angew. Chem. Int. Ed.2012,51, 9226-9237. (review, invited contribution).

16. Chong Qin, Wang Zhou, Feng Chen, Yang Ou, andNing Jiao*, Iron-catalyzed C-H and C-C Bond Cleavage: A Direct Approach to Amides from Simple Hydrocarbon Molecules,Angew. Chem. Int. Ed.2011,50, 12595-12599.

17. Feng Chen, Chong Qin, Yuxin Cui, andNing Jiao*, Implanting 氮 into Hydrocarbon Molecules via C-H/C-C Bonds Cleavage: The Direct Approach to Tetrazoles.Angew. Chem. Int. Ed.2011,50, 11487-11491. (Highlighted bySynfacts(Synfacts,2012,8, 0144.).

18. Chun Zhang, Zejun Xu, Liangren Zhang, andNing Jiao*, 銅catalyzed Aerobic Oxidative 耦合 of Aryl Acetaldehydes with Anilines Leading to α-Ketoamides.Angew. Chem. Int. Ed.2011,50, 11088-11092. (VIP articles, Frontispiece Paper, Highlighted byChemCatChem(ChemCatChem,2012,4, 175-176)

19. Shengtao Ding, andNing Jiao*, The Direct Transformation of DMF (N,N-Dimethylformamide) to -CN: Pd-catalyzed Cyanation of Heteroarenes via C-H Functionalization.J. Am. Chem. Soc.2011,133(32), 12374-12377. (Highlighted byOrg. Process Res. Dev.2011,15, 1216–1221).

20. Chong Qin, andNing Jiao*, Iron-Facilitated Direct Oxidative C?H Transformation of Allylarenes or 烯烴 to Alkenyl Nitriles.J. Am. Chem. Soc.2010,132, 15893-15895. (Most accessed articles, Highlighted bySynfacts(Synfacts,2011,2, 203))

21. Chun Zhang, andNing Jiao*, 銅catalyzed Aerobic Oxidative Dehydrogenative 耦合 of Anilines Leading to Aromatic Azo Compounds using Dioxygen as Oxidant.Angew. Chem. Int. Ed.2010,49, 6174-6177. (Most accessed articles)

22. Zhuangzhi Shi,Bo Zhang, Yuxin Cui, andNing Jiao*, PalladiumCatalyzed 圓環expansion Reaction of Indoles with Alkynes: From Indoles to Tetrahydroquinoline Derivatives Under Mild Conditions.Angew. Chem. Int. Ed.2010,49, 4036-4041. (Frontispiece Paper, Most accessed articles)

23. Chun Zhang, andNing Jiao*, Dioxygen Activation at Ambient Conditions: 銅catalyzed Oxidative Amidation-Diketonization of Terminal Alkynes Leading to α-Ketoamides.J. Am. Chem. Soc.2010,132, 28-29. (Highlighted byOrg. Chem.)

24. Zhuangzhi Shi,Shengtao Ding, Yuxin Cui, andNing Jiao*, Pd-catalyzed Oxidative Cycloaromatization of Biaryls with Alkynes Using Dioxygen as Oxidant.Angew. Chem. Int. Ed.2009,48, 7895-7898.

25. Wang Zhou, Liangren Zhang, andNing Jiao*, Direct Transformation of 甲基 Aromatics to Aryl Nitriles at Room 溫度Angew. Chem. Int. Ed.2009,48, 7094-7097. (Hot Paper) (Highlighted by “Synform,2009,A71”, “Org. Chem. Highlights” (2010, September 27), and “Nature China ”.

26. Zhuangzhi Shi, Chun Zhang, Si Li, Delin pan, Sengtao Ding, Yuxin Cui, andNing Jiao*, Indoles from Simple Anilines and Alkynes: PalladiumCatalyzed C-H Activation Using Dioxygen as the Oxidant.Angew. Chem. Int. Ed.2009,48, 4572-4576. (Hot Paper, Highlighted bySynfacts(Synfacts,2009,8, 846)，and“Nature China ”, Most accessed articles).

27. Delin pan, Anjun Chen, Yijin Su, Wang Zhou, Si Li, Wei Jia, Juan Xiao, Qingjian Liu, Liangren Zhang, andNing Jiao*,Ligand Free Pd-Catalyzed Highly Selective Arylation of Allylic Esters with Retention of the Traditional Leaving 基團Angew. Chem. Int. Ed.2008,47, 4729-4732.