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沈增明
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沈增明,女,1977年出生于柯橋區(qū),現(xiàn)為上海交通大學(xué)化學(xué)化工學(xué)院教授、博士生導(dǎo)師。2001年至2006年在中科院上海有機(jī)化學(xué)研究所攻讀碩博學(xué)位,師從陸熙炎院士。2006年至2008年在多倫多大學(xué)化學(xué)系進(jìn)行博士后研究。自2010年起,沈增明在上海交通大學(xué)化學(xué)化工學(xué)院擔(dān)任副教授,2018年1月起晉升為教授。本科生主要教《有機(jī)化學(xué)》這門學(xué)科,而研究生主要教授《現(xiàn)代有機(jī)合成》。研究方向有以下三個(gè):金屬催化的新型有機(jī)反應(yīng)研究;金屬催化的不對稱反應(yīng)的研究;雜環(huán)化合物的研究。

人物履歷

教育經(jīng)歷

1997-2001:四川師范大學(xué)化學(xué)系,學(xué)士

2001-2006:中國科學(xué)院上海有機(jī)化學(xué)研究所,碩博(導(dǎo)師:陸熙炎院士)

2006-2008:多倫多大學(xué)化學(xué)系,博士后

工作經(jīng)歷

2010-2018.1:上海交通大學(xué)化學(xué)化工學(xué)院,副教授,碩士生導(dǎo)師

2018.1-至今:上海交通大學(xué)化學(xué)化工學(xué)院,教授、博士生導(dǎo)師

個(gè)人成果

科研項(xiàng)目

催化的C—H鍵官能團(tuán)化實(shí)現(xiàn)交叉偶聯(lián)反應(yīng),國家中華人民共和國國家自然科學(xué)基金委員會(huì)青年科學(xué)基金 .01-2012.12,已結(jié)題。

入選2009年度上海市浦江人才計(jì)劃 2009.7-2011.7,已結(jié)題。

惰性C-H鍵在廉價(jià)金屬銅催化下的反應(yīng)性研究,上海交通大學(xué)校長機(jī)動(dòng)費(fèi)研究基金,2011.1-2013.12。

銅催化的C-C鍵斷裂反應(yīng)的研究,國家自然科學(xué)基金面上項(xiàng)目 2013.1-2016.12。

銅催化的C-C鍵斷裂反應(yīng)的研究,上海市教委創(chuàng)新重點(diǎn)項(xiàng)目 2013.1-2015.12。

代表論文

1. Li, Xiaomeng; Guo, Yunlong; Shen, Zengming* J. Org. Chem. 2018, 83, 2818.

2. Cruz, Faben A.; Zhu, Yamin; (并列一作,按字母順序排列) Tercenio, Quentin D.; Shen, Zengming*, 越南盾, Vy M.* “Alkyne Hydroheteroarylation: nantioselective Coupling of Indoles and Alkynes via Rh-Hydride Catalysis” J. Am. Chem. Soc. 2017, 139, 10641-10644.

3. Zhu, Yamin; Shen, Zengming* “Copper-Catalyzed Acyloxycyanation of Alkynes with Acetonitrile: Regioselective Construction of Cyclic Acrylonitriles by 6-endo or 5-EXO Cyclization” Adv. Synth. Catal. 2017, 359, 3515.

4. Lu, Wenkui; Xu Hui; Shen Zengming* “Copper-catalyzed aromatic C–H alkoxylation with alcohols under aerobic conditions” Org. Bio摩爾 Chem., 2017, 15, 1261–1267.

5. Yu, Zhengwei; Li, Linyi; Shen, Zengming* “Cu-Catalyzed Cyanation of Aryl Iodides with Acetonitrile as Cyano Source” Chin. J. Org. Chem. 2017, 37, 1273-1277.

6. Zhang Wei; Yang, Shiping; Shen, Zengming* “Copper-Catalyzed Cyanomethylation of Substituted Tetrahydroisoquinolines with Acetonitrile” Adv. Synth. Catal. 2016, 358, 2392– 2397.

7. Zhao, Mengdi; Zhang, Wei; Shen, Zengming* “Cu-Catalyzed Cyanation of Indoles with Acetonitrile as a Cyano source” J. Org. Chem. 2015, 80, 8868.

8. Li, Linyi; Yu, Zhengwei; Shen, Zengming*; “Copper-Catalyzed Aminoxylation of Different Types of Hydrocarbons with TEMPO: A Concise Route to N-Alkoxyamine Derivatives” Adv. Syn. cat 2015, 357, 3495.

9. Zhu, Yamin; Li, Linyi; Shen, Zengming* “Cu-Catalyzed Cyanation of Arylboronic Acids with Acetonitrile: A Dual Role of TEMPO” Chem. Eur. J. 2015, 21, 13246.(Highlighted as a cover.)

10. Zhu, Yamin; Zhao, Mengdi; Lu, Wenkui; Li, Linyi; Shen, Zengming* “Acetonitrile as a Cyanating Reagent: Cu-Catalyzed Cyanation of Arenes” Org. Lett. 2015, 17, 2602. (Highlighted by Synform. See: Synform 2015, 10, A144–A145.)

11. Xu, Hui; Qiao, Xixue; Yang, Shiping; Shen, Zengming* “Cu-Catalyzed Direct Amidation of Aromatic C?H Bonds: An Access to Arylamines” J. Org. Chem. 2014, 79, 4414.

12. Kou, Xuezhen; Zhao, Mengdi; Qiao, Xixue; Zhu, Yamin; Tong, Xiaofeng; Shen, Zengming* “Copper-Catalyzed Aromatic C-H Bond Cyanation by C-CN Bond Cleavage of Inert Acetonitrile” Chem. Eur. J. 2013, 19, 16880-16886. (Highlighted as a frontispiece.)

13. Mo Song, Zhu Yamin, Shen Zengmging*, “Copper-catalyzed aromatic C–H bond halogenation with lithium halides under aerobic conditions” Org. Bio摩爾 Chem. 2013, 11, 2756-2760. (Hot Paper, highlighted as a cover.)

14. Kou Xuezhen, Fan Jiajun, Tong Xiaofeng, Shen Zengming*, “Recent Progress in the Research of Transition Metal-Catalyzed C-CN Bond Cleavage” Chin. J. Org. Chem. 2013, 33, 1407-1422.

15. Shen, Zengming*; Ni, Zhenjie; Mo, Song; Wang, Jing; Zhu, Yamin; “PalladiumCatalyzed Intramolecular Decarboxylative Coupling of Arene Carboxylic Acids/Esters with Aryl Bromides” Chem. Eur. J. 2012, 18, 4859-4865.

16. Wang, Ruiping; Mo, Song; Lu, Yongzhong; Shen, Zengming*; “Domino Sonogashira Coupling/Cyclization Reaction Catalyzed by Copper and ppb Levels of Palladium: A Concise Route to Indoles and Benzo[b]furans” Adv. Synth. Catal. 2011, 353, 713-718.

17. Lu, Yongzhong; Wang, Ruiping; Qiao, Xixue; Shen, Zengming*; “Copper-Catalyzed Aromatic C–H Bond Halogenation Using Lithium Halides as Halogenating Reagents” Synlett, 2011, 1038. (the special issue of Synlett dedicated to Professors Xiyan Lu and Li-Xin Dai).

18. Shen, Zengming; Dornan, Peter K.; Khan, Hasan A; Woo, Tom; Dong, Vy M. “Mechanistic Insights into the Rhodium-Catalyzed Intramolecular Ketone Hydroacylation” J. Am. Chem. Soc. 2009, 131, 1077-1091.

19. Shen, Zengming; Dong, Vy M. “Benzofurans Prepared by C-H Bond Functionalization with Acylsilanes” Angew. Chem. Int. Ed. 2009, 48, 784-786. (For a highlight, see: Synfacts, 2009, 4, 409)

20. Shen, Zengming; Khan, Hasan A.; Dong, Vy M. “Rh-Catalyzed Carbonyl Hydroacylation: An Enantioselective Approach to Lactones” J. Am. Chem. Soc. 2008, 130, 2916-2917.

· (See the highlight in 化學(xué) World featuring this work: James Mitchell Crow, "Rhodium fast tracks route to lactones." Editorial Board of SYNFACTS selects this article as the Synfact of the month, see: Synfacts, 2008, 5, 485).

21. Shen, Zengming; Lu, Xiyan; “Cupric Halide-Mediated Intramolecular Halocyclization of N-Electron-Withdrawing Group-Substituted 2-Alkynylanilines for the Synthesis of 3-Haloindoles” Adv. Synth. Catal. 2009, 351, 3107-3112.

榮譽(yù)獎(jiǎng)勵(lì)

1、2006年獲“中國科學(xué)院大學(xué)優(yōu)秀畢業(yè)生”稱號(hào)

2、2009年獲“上海市浦江人才計(jì)劃”

3、2010年獲上海交通大學(xué)“SMC-晨星青年學(xué)者獎(jiǎng)勵(lì)計(jì)劃”優(yōu)秀青年教師B類

4、2013年度三年聘期工作考核“優(yōu)秀”

5、2016年和2017年教職工年度述職考核“優(yōu)秀”

6、首屆上海交通大學(xué)“教書育人獎(jiǎng)”提名獎(jiǎng)(2017)

7、第二屆上海高校青年教師教學(xué)競賽“二等獎(jiǎng)”(2016)

8、上海交通大學(xué)首屆青年教師教學(xué)競賽“一等獎(jiǎng)”(2016)

9、上海交通大學(xué)教學(xué)能手稱號(hào)(2016)

10、上海交通大學(xué)優(yōu)秀教師“二等獎(jiǎng)”(2016)

11、上海交通大學(xué)“SMC-晨星青年學(xué)者獎(jiǎng)勵(lì)計(jì)劃”優(yōu)秀青年教師A類和B類(2017/2010)

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