江中興，博士、教授、武漢大學藥學院博士生導師、楚天學者特聘教授。
在研項目： “基于單一分子量聚乙二醇的生物材料的設計、合成及其在生物大分子藥物研發中的應用”，國家自然科學基金面上項目，批準號21572168，65萬元，2016年-2019年； “F-19 MRI 可視化5-FU 傳輸載體的合成與應用研究”，國家自然科學基金面上項目，批準號21372181，78萬元，2014年-2017年； “含樹枝狀大分子顯影材料的制備與應用”，東華大學纖維材料改性國家重點實驗室開放課題，10萬元，2015年-2017年； “鹽霉素的結構改造及活性研究”，中科院天然產物有機合成化學重點實驗室開放課題，3萬元，2015年-2016年
在SCI期刊上發表文章30余篇，文章被引用600余次，H-index>14；申請美國專利4項，中國專利獎4項，其中2項美國專利及1項中國專利已經獲的授權；任Journal of Biomolecular Research & Therapeutics編委，受邀為Bioconjugate 化學，Journal of Organic Chemistry，Journal of 螢石 Chemistry等10余個英文學術期刊審稿人，相關研究成果被Faculty of 1000, F-blog, RSC Advances等多次評述；主持國家自然科學基金面上項目等多個研究項目，指導多個國家級大學生創新創業項目.
基本情況
學習簡歷
1995年9月至1999年7月 西南大學化學化工學院獲學士
1999年8月至2004年7月 中科院上海有機化學研究所獲博士學位
工作簡歷
2004年8月至2007年4月 猶他大學藥學院博士后
2007年4月至2008年8月 美國印第安納大學醫學院博士后
2008年8月至2011年10月 馬里蘭大學藥學院研究助理教授
2011年10月至今 武漢大學藥學院教授
主要研究方向及業績
研究方向
藥物化學，有機化學，分子影像學，新型生物材料，藥物的可視化傳輸與緩釋
業績概要
在SCI期刊上發表文章31篇，文章被引用550余次，H-index>12；申請美國專利4項，中國專利獎3項，其中3項美國專利已經獲批；任 Journal of Biomolecular Research & Therapeutics 編委，相關研究成果被Faculty of 1000, F-blog, RSC Advances等多次評述。
主要科研專利及論著
批準專利及專利申請
1. Yu Y.B., Jiang Z.-X. “Highly fluorinated ?-amino acids and methods of making and using same”美國專利號 US 8,052,961B2
2. Yu Y.B., Jiang Z.-X. “Highly fluorinated oils and surfactants and methods of making and using same”美國專利號 US 8,252,778B2
3. Yu Y.B., Jiang Z.-X., Xiao N. “Protected enantiopure trifluorothreonines and methods of making and using same”申請號 PCT/US2007/078552，國際公開號 WO2008034095
4. Yu Y.B., Jiang Z.-X.“Conjugates of F MR imaging tracers for use in multi-chromic MRI imaging”申請號 PCT/US2009/63381
5. 江中興，張華，李學飛，李昱“一種單一分子量聚乙二醇及其衍生物的合成方法” CN201310710498.6
6. 江中興，李學飛，李昱，夏桂全“一種新型大環環硫酸及其制備方法與運用”CN201310656494.4
7. 江中興，余偉江，薄少偉“一種樹枝狀大分子氟-19磁共振顯影劑及其制備方法和應用” CN20150037920.5
發表專著
Jiang Z.-X., Li X., Qing F.-L. “A green 化學 strategy: fluorous catalysis” Book chapter in “Bridging Heterogeneous and Homogenous Catalysis” Edited by Li C., Liu Y. Wiley-VCH，p253-282, 2014.
發表文章
1.Yu W., Yang Y., Bo S., Li Y., Chen S., Yang Z., Zheng X., Jiang Z.-X.*, Zhou X. “The 設計 and Synthesis of Fluorinated Dendrimers for Highly Sensitive F MR” J. Org. Chem. 2015, in print (IF 4.64).
2.Zhang H., Li X., Shi Q., Li Y., Xia G., Chen L., Yang Z., Jiang Z.-X.* “Highly efficient synthesis of monodisperse poly(乙烯 glycols) and derivatives through macrocyclization of oligo(ethylene glycols)” Angew. Chem. Int. Ed. 2015, DOI: 10.1002/anie.201410309 (IF 11.34).
3.Taraban M. B., Li Y., Yue F., Jouravleva E. V., Anisimov M. A., Jiang Z.-X., Yu Y. B.* “Conformational transition of a non-associative fluorinated amphiphile in aqueous solution” RSC Adv. 2014, 4(97), 54565-54575.
4.Xia G., Li Y., Li Y., Li X., Zhang H., Yu Y. B., Jiang Z.-X.* “Optimize the separation of fluorinated amphiles using high-performance liquid chromatography” J. Fluorine Chem. 2014, 165, 39-42.
5.Li Y., Guo Q., Li X., Zhang H., Yu F., Yu W., Xia G., Fu M., Yang Z., Jiang Z. -X.* “Fluorous synthesis of mono-dispersed poly(乙烯 glycols)” Tetrahedron Lett. 2014, 55，2110-2113.
6.Jiang Z.-X., Zhi S., Zhang W.* “Recent progress on fluorous synthesis of biologically interesting compounds” 摩爾 Divers. 2014, 18, 203-218.
7.Li Y., Thapa B., Zhang H., Li X., Yu F., Jeong E.-K., Yang Z., Jiang Z.-X.* “Synthesis of gemini surfactants with twelve symmetric fluorine atoms and one singlet F MR signal as novel F MRI agents” Tetrahedron 2013, 69, 9586-9590.
8.Zhang H., Li Y., Jiang Z.-X.* “Fluorine is flourishing in pharmaceuticals” J. Bio摩爾 Res. Thera. 2012, 1:e107.
9.Yu Y. B.,* Jiang Z.-X. “Prospect of F MRI-guided drug delivery” J. Pharm. Drug Deliv. Res. 2012, 1, 1
10.Jiang Z.-X., Feng Y., Yu Y.B.* “Fluorinated paramagnetic chelates as potential multi-chromic F tracer agents” Chem. Comm. 2011, 47, 7233-7235.
11.Jiang Z.-X., Yu Y.B.* “Fluorous mixture synthesis of asymmetric dendrimers” J. Org. Chem., 2010, 75, 2044–2049.
12.He R., Yu Z., He Y., Zeng L.-F., Xu J., Wu L., Gunawan A. M., Wang L., Jiang Z.-X., Zhang Z.-Y.* "Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor" ChemMedChem, 2010, 5, 2051-2056.
13.Zhang X., He Y., Liu S., Yu Z., Jiang Z.-X., Yang Z., 越南盾 Y., Nabinger S.C., Wu L., Gunawan A.M., Wang L., Chan R.J., Zhang Z.-Y.* “Salicylic acid-based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) ” J. Med. Chem., 2010, 53, 2482–2493.
14.Zhang X.,* Fan S., He C.-Y., Wan X., Min Q.-Q., Yang J., Jiang Z.-X. “Pd(OAc) Catalyzed olefination of highly electron-deficient perfluoroarenes” J. Am. Chem. Soc., 2010, 132, 4506–4507.
15.Jiang Z.-X., Liu X., Jeong E.-K., Yu Y.B.* “Symmetry-guided 設計 and fluorous synthesis of a stable and rapidly excreted imaging tracer for F MRI” Angew. Chem. Int. Ed. 2009, 48, 4755-4758.
16.Jiang Z.-X., Zhang Z.-Y.* “Targeting PTPs with small molecule inhibitors in cancer treatment” Cancer and Metastasis Reviews. 2008, 27, 263-272.
17.Jiang Z.-X., Yu Y.B.* “The 設計 and synthesis of highly branched and spherically symmetric fluorinated macrocyclic chelators” Synthesis. 2008, 2, 215-220.
18.Liu S., Zhou B., Yang H., He Y., Jiang Z.-X., Kumar S., Wu, L., Zhang Z.-Y.* “Aryl vinyl sulfones and sulfonates as active site-directed and mechanism-based probes for protein tyrosine phosphatases” J. Am. Chem. Soc. 2008, 130, 8251-8260.
19.Jiang Z.-X., Yu Y.B.* “The 設計 and synthesis of highly branched and spherically symmetric fluorinated oils and amphiles” Tetrahedron. 2007, 63, 3982-3988.
20.Jiang Z.-X., Yu Y.B.* “The synthesis of a geminally perfluoro-tert-butylated b-amino acid and its protected forms as a potential pharmacokinetic modulator and reporter for peptide-based pharmaceuticals” J. Org. Chem. 2007, 72, 1464-1467.
21.Wang B.-L., Jiang Z.-X., You Z.-W., Qing F.-L.* “Total synthesis of trifluoromethylated analogs of macrosphelide A” Tetrahedron. 2007, 63, 12671-12680.
22.Xiao N., Jiang Z.-X., Yu Y.B.* “Enantioselective synthesis of (2R, 3S)- and (2S, 3R)-4,4,4- trifluoro-N-Fmoc-O-tert-butyl-threonine and their racemization-free incorporation into oligopeptides via solid-phase synthesis” Biopolymers (Peptide Science). 2007, 88, 781-796.
23.You Z.-W., Jiang Z.-X., Wang B.-L., Qing F.-L.* “An efficient and general route to gem-difluoromethylenated a,b-unsaturated d-lactones: high enantioselective synthesis of gem- difluoromethylenated goniothalamins” J. Org. Chem. 2006, 71, 7261-7267.
24.Wang B.-L, Yu F., Qiu X.-L., Jiang Z.-X, Qing F.-L.* “Synthesis of trifluoromethylated analogues of b-L-fucofuranose and b-L-4, 6-dideoxyxylohexopyranose” J. Fluorine Chem. 2006, 127, 580-587
25.Jiang Z.-X., Liu X.-P., Qiu X.-L., Qing F.-L.* “Asymmetric synthesis of both enantiomers of syn-3-(trifluoromethyl)cysteine derivatives” J. Fluorine Chem. 2005, 126, 499-505.
26.Jiang Z.-X., Qing F.-L.* “Regioselective and stereoselective nucleophilic ring opening of trifluoromethylated cyclic sulfates: asymmetric synthesis of both enantiomers of syn-(3-trifluoromethyl)isoserine” J. Org. Chem. 2004, 69, 5486-5489.
27.Jiang Z.-X., Qin Y.-Y., Qing F.-L.* “Asymmetric synthesis of both enantiomers of anti-4,4,4-trifluorothreonine and 2-amino-4,4,4-trifluorobutanoic acid” J. Org. Chem. 2003, 68, 7544-7547.
28.Jiang Z.-X., Qing F.-L.* “Sodium carbonate as carbon dioxide source for the synthesis of cyclic carbonates containing the trifluoromethyl group” J. Fluorine Chem. 2003, 123, 57-60.
29.Qing F.-L.,* Jiang Z.-X. “Synthesis of trifluoromethylated b-and g-lactones through the Palladiumcatalyzed cyclocarbonylation” J. Fluorine Chem. 2002, 114, 177-180.
30.Jiang Z.-X., Qing F.-L.* “Palladium-catalyzed cyclocarbonylation of trifluoromethyl propargylic alcohols producing 3-trifluoromethyl-2(5H)-furanones (g-lactones)” Tetrahedron Lett. 2001, 42, 小行星90519053.
31.Qing F.-L.,* Jiang Z.-X. “Palladium-catalyzed cyclocarbonylation of (Z)-3-iodo-3- trifluoromethyl allylic alcohols producing 3-trifluoromethyl-2(5H)-furanones (g-lactones)” Tetrahedron Lett. 2001, 42, 5933-5935.
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