劉汝濤，1972年1月生，山東沂水人，中共黨員，教授，理學(xué)博士，博士生導(dǎo)師。2002年6月畢業(yè)于山東大學(xué)化學(xué)與化工學(xué)院，獲理學(xué)博士學(xué)位。同年6月赴美國(guó)Yeshiva大學(xué)愛(ài)因斯坦醫(yī)學(xué)院生理與生物物理系，從事博士后研究，師從國(guó)際著名生物物理學(xué)家Mark R. Chance教授。2005年9月作為高層次優(yōu)秀人才引入山東大學(xué)環(huán)境科學(xué)與工程學(xué)院工作。
人物成就
主要利用PCR擴(kuò)增、基因序列分析，凝膠電泳，光譜技術(shù)，電視顯微電泳技術(shù)，液相色譜-質(zhì)譜聯(lián)用技術(shù)等手段從事小分子與蛋白質(zhì)、核酸相互作用及大分子結(jié)構(gòu)、功能及環(huán)境污染與健康領(lǐng)域的研究工作。已發(fā)表論文38篇，其中第一作者SCI論文25篇，單篇論文影響因子達(dá)9.624。發(fā)表的論文已被Cell；Acct. Chem. Res.； 摩爾 Cell & Proteomics等國(guó)際著名刊物引用200余次。
學(xué)術(shù)兼職
美國(guó)質(zhì)譜學(xué)會(huì)成員
紐約自然科學(xué)院成員
國(guó)際生物物理學(xué)會(huì)成員
美國(guó)生物化學(xué)與分子生物學(xué)學(xué)會(huì)成員
美國(guó)Brookhaven國(guó)家重點(diǎn)實(shí)驗(yàn)室客座研究員
Biochime等國(guó)際著名學(xué)術(shù)榜刊物的稿件特約評(píng)審員
研究領(lǐng)域
環(huán)境污染與健康：主要包括環(huán)境化學(xué)污染物對(duì)機(jī)體的損傷、致病以及污染物在蛋白質(zhì)和/或基因分子水平上的毒性作用機(jī)理、關(guān)鍵修復(fù)技術(shù)及預(yù)防對(duì)策等的研究；
環(huán)境分析化學(xué)：開(kāi)發(fā)環(huán)境化學(xué)污染物的高靈敏度、高選擇性監(jiān)測(cè)方法，研究環(huán)境化學(xué)污染物在環(huán)境、機(jī)體中的存在形態(tài)、遷移轉(zhuǎn)化與富集規(guī)律及生物標(biāo)志物等領(lǐng)域的研究；
持久性有機(jī)污染物降解機(jī)理及工藝：探討持久性有機(jī)污染物的高級(jí)氧化降解機(jī)理，開(kāi)發(fā)高效率、低能耗的降解工藝；
清潔發(fā)展機(jī)制(CDM)；清潔生產(chǎn)技術(shù)及工藝(CP Technology)。
主講課程：
《環(huán)境毒理學(xué)》，《環(huán)境化學(xué)》，《環(huán)境檢測(cè)》，《專業(yè)英語(yǔ)》等。
科研獎(jiǎng)勵(lì)
1.國(guó)際獎(jiǎng)勵(lì)：2002年獲國(guó)際技術(shù)教育委員會(huì)杰出論文獎(jiǎng)。
2.省級(jí)獎(jiǎng)勵(lì)：2001年獲山東省優(yōu)秀碩士學(xué)位論文獎(jiǎng)；
2000年獲“挑戰(zhàn)杯”山東省一等獎(jiǎng)。
3.校級(jí)獎(jiǎng)勵(lì)：1998年獲山東大學(xué)校長(zhǎng)獎(jiǎng)學(xué)金；
2000年被評(píng)為山東大學(xué)學(xué)生科技創(chuàng)新先進(jìn)個(gè)人；
2001年獲山東大學(xué)最高額獎(jiǎng)學(xué)金—立青獎(jiǎng)學(xué)金；
2003年獲山東大學(xué)優(yōu)秀博士學(xué)位論文獎(jiǎng)。
資格證書
2002年獲美國(guó)Yeshiva大學(xué)愛(ài)因斯坦醫(yī)學(xué)院環(huán)境健康與安全評(píng)價(jià)證書；
2004年獲美國(guó)Yeshiva大學(xué)愛(ài)因斯坦醫(yī)學(xué)院廢棄物處理與安全評(píng)價(jià)證書；
2005年獲美國(guó)Yeshiva大學(xué)愛(ài)因斯坦醫(yī)學(xué)院生理與病理學(xué)培訓(xùn)證書；
2005年獲美國(guó)質(zhì)譜學(xué)會(huì)培訓(xùn)證書。
發(fā)表論文
1. Rutao Liu, Olga Zak, Philip Aisen, Mark R. Chance, “Structure of full-length transferrin-transferrin receptor and the iron transportation mechanism with 毒理學(xué)”, 2006, (In Preparation)
2. Lijun Ren, Xueliang Yuan, Rutao Liu*, “Research on method development during the strategic environmental assessment”, Stoch Environ Res Risk Assess, 2006, (SCI, 電子版已發(fā)表)
3. Hua Sui, Gang Zheng, Yuanyuan Zhang, Rutao Liu*, Ganzuo Li, “Synthesis of Ferromagnetic in Detergent Solution”, J Dispersion Science Technology，2006，27(3):311-315(SCI)
4. Guozhong Xu, Rutao Liu, Olga Zak, Philip Aisen, Mark R. Chance, “Structural Allostery and Binding of the Transferrin-Receptor Complex”, 摩爾 & Cellular Proteomics, 2005，4(12): 1959-1967(并列第一作者，影響因子Ip=9.624,該研究成果被選為刊物的封面重點(diǎn)介紹)
5. Rutao Liu, Jinghe Yang, Changxai Sun, Xia Wu, Zengjun Lan, Tao Wu, “Resonance Double Light Scattering Method for the Determination of Nucleic Acids with Cetylpyridine 溴化物”, Mikrochimica Acta, 2004, 147(1-2): 105-109. (SCI)
6. Rutao Liu, Jinghe Yang, Changxia Sun, Xia Wu, Lei Li and Benyu Su, “Study on the interaction between nucleic acids and cationic surfactants”, Colloids and surfaces B-Biointerfaces, 2004, 34(1): 59-63. (SCI)
7. Rutao Liu, Jing-Qu Guan, Olga Zak, Philip Aisen, Mark R. Chance, “Structural Reorganization of the Transferrin C-lobe: Transferrin C-lobe Binds to the Receptor Helical Domain”, Biochemistry, 2003, 42: 12447-12454 (Accelerated Publication; Cell, 2004,116: 483-489, Preview 及Cell, 2004,116: 565-576對(duì)該成果專門評(píng)論; Ip=4.064).
8. Rutao Liu, Jinghe Yang, Changxia Sun, Lei Li, Xia Wu, Zhengmin Li, Chuansong Qi, “Study of the interaction of nucleic acids with acridine orange-CTMAB and determination of nucleic acids at nanogram levels based on the enhancement of resonance light scattering”, Chemical Physics Letters, 2003, 376: 108-115.(Ip=2.438)
9. Rutao Liu, Jinghe Yang, Changxia Sun, Xia Wu, Lei Li, Zhengmin Li, “Resonance light-scattering method for the determination of BSA and HSA with sodium dodecyl benzene sulfonate or sodium lauryl sulfate”, Analytical and Bioanalytical Chemistry, 2003, 377(2): 375-379. (Ip=2.098)
10. Rutao Liu, Jinghe Yang, Xia Wu, “Study of the interaction between nucleic acid and oxytetracycline- Eu3+ and its analytical application”, J. Lumin., 2002, 96: 201-209. (SCI)
11. Rutao Liu, Jinghe Yang, Xia Wu, Zhengmin Li, Fang Huang, “Resonance Rayleigh Light -scattering of Thiamine Hydrochloride-nucleic acid-CTMAB systems and their analytical application”, Journal of Trace and Microprobe Techniques, 2002, 20(3), 363-376. (SCI)
12. Rutao Liu, Jinghe Yang, Xia Wu, Zengjun Lan “Resonance Double Light Scattering Method for the Determination of Proteins with Morin-CTMAB”, Spectrochim. Acta, Part A, 2002, 20(3), 363-376. (SCI)
13. Rutao Liu, Jinghe Yang, Xia Wu, Changxia Sun, “Study on the Resonance Light Scattering Spectrum of 小檗堿Cetyltrimethylammonium Bromide System and the Determination of Nucleic Acids at Nanogram Levels”, Spectrochim. Acta, part A, 2002, 58/3:459-467 (SCI)
14. Rutao Liu, Jinghe Yang, Xia Wu, “Interaction of cetyl 吡啶 bromide with nucleic acids and determination of nucleic acids at nanogram levels based on the enhancement of resonance Rayleigh light scattering”, Spectrochimica Acta Part A, 2002, 58(9): 1935-1942. (SCI)
15. Rutao Liu, Canzhu Gao, Jinghe Yang, “Study on the High corrosion Resistance and Long Life-span Process of Electroless Nickel”, Metal Finishing, 2002, 100(3): 34-37. (EI)
16. Rutao Liu, Jinghe Yang, Xia Wu, Changxia Sun, Tao Wu, “Interaction of Morin-CTMAB with Nucleic Acids and Determination of Nucleic acids at Nanogram Per Milliliter Levels Based on the Enhancement of Preresonance Light Scattering”, The Analyst, 2001, 126:1367-1371. (Ip=2.789)
17. Rutao Liu, Jinghe Yang, Xia Wu, Tao Wu, “Resonance double 頻率 light scattering of morin- nucleic acid-CTMAB system and their analytical application”, Analytical Chimica Acta, 2001, 448(1-2):85-91. (Ip=2.588)
18. Rutao Liu, Jinghe Yang, Xia Wu, Changxia Sun, “Interaction of CTMAB with nucleic acids and determination of nucleic acids at nanogram levels based on the measurement of light scattering”, Analytical Chimica Acta, 2001,441/2:303-308. (Ip=2.588)
19. Rutao Liu, Jinghe Yang, Xia Wu, Sui Hua, Changxia Sun, “Interaction of morin with CTMAB: Aggregation and location in micellar”, Spectrochim. Acta, Part A, 2001, 57/13:2561-2566. (SCI)
20. Rutao Liu, Jinghe Yang, Xia Wu, Changxia Sun, “Simple and sensitive determination of nucleic acid by Rayleigh light scattering technique with methyl green-CTMAB”, Indian J. of Chem., 2001, 40A: 1121-1123. (SCI)
21. Rutao Liu, Canzhu Gao, Sui Hua, Yanqing Feng, Jinghe Yang, “Rapid spectrometric Determination of Ni2+ in Electroless Nickel Deposition Baths Containing Fe”，Plating and surface Finishing, 2001, 88(9): 80-83. (SCI)
22. Rutao Liu, Guan, J-Q., Aisen, P., Chance, M.R. “Human Transferrin Binding Sites with Transferrin Receptor Detected by Hydroxyl Radical Footprinting and 質(zhì)量 Spectrometry”，Biophysical Journa，2004, 86: 96a. (SCI)
23. Chance, M.R., Zak, O., Aisen, P., Rutao Liu, and J-Q.Guan, “Structure of Transferrin: Receptor Complex as Analyzed by Footprinting and Mass Spectrometry”, J. Am. Soc. 質(zhì)量 Spectrometry, 2004, 15:63S. (SCI)
24. Rutao Liu, Zak, O., Aisen, P., Chance, M.R.，“Structural Reorganization of Transferrin C-Lobe and Transferrin Receptor Upon Complex Formation: C-Lobe Binds to the Receptor Helical Domain”, 摩爾 & Cellular Proteomics, 2003, 2.9 supplement, 45.1. (SCI)
25. Rutao Liu., Aisen, P., Zak, O., Chance, M.R., “Synchrotron Hydroxyl Radical Footprinting and 質(zhì)量 Spectrometry Method to Probe the surface of Human Transferrin C-Lobe”, Biophysical Journal, 2003, 84: 36A. (SCI)
26. Rutao Liu, Canzhu Gao, Sui Hua, Jinghe Yang, Yuli Lu,“Derivation and Rapid Spectrophotometric Determination of iron in Electroless Nickel Plating solution”, Plating and surface Finishing, 2000，87(2): 73-77. (SCI)
27. Rutao Liu, Canzhu Gao, and Yuli Lu, “Study on a medium speed and long life-span electroless nickel plating process”, Transactions of the Institute of Metal Finishing ,2000, 78(5): 198-200. (SCI)
28. Cunguo Lin, Jinghe Yang, Xia Wu, Guiling Zhang, Rutao Liu, Xihui Cao, Rongjiang Han, “Enhanced fluorescence of the terbium-gadolinium-nucleic acids system and the determination of nucleic acids”, Anal. Chim. Acta, 2000, 403:219- 224. (SCI)
29. Fang Huang, Jinghe Yang, Aiyou Hao, Xia Wu, Rutao Liu，Quanli Ma, “The Study of Spectrographic Properties and Molecular Recognition of Calix[n]arenes”, Spectrochim. Acta, Part A, 2001, 57:1025-1030. (SCI)
30. Canzhu Gao, Yuli Lu, Rutao Liu, “Influence of Additives on Electrodeposition of Nickel from a Watts Bath－a Cyclic Voltammetric study”, Plating and surface Finishing, 1997, 84(9):83-85. (SCI)
31. 劉汝濤, 馮雁卿，高燦柱, 楊景和，“化學(xué)鍍清潔生產(chǎn)工藝的研究”，化工環(huán)保, 2001, 3:164-167.
32. 劉汝濤, 高燦柱, 楊景和，鹿玉理，“化學(xué)鍍鎳液中NaH-2PO-2的快速測(cè)定”，,電鍍與環(huán)保, 2000, 20(1),29-31.
33. 劉汝濤, 張繼有, 高燦柱, 鹿玉理，“化學(xué)鍍鎳穩(wěn)定性因素的研究”，表面技術(shù)，2001，31(1): 10-12.
34. 劉汝濤, 高燦柱, 鹿玉理，“化學(xué)鍍鎳添加工藝的研究”，電鍍與環(huán)保，1998，18(5):19－21.
35. 劉汝濤, 高燦柱, 隋華, 鹿玉理，“化學(xué)鍍鎳液中鎳離子濃度得快速測(cè)定”，材料保護(hù)，1998, 31(10):25－27.
36. 劉汝濤, 高燦柱, 隋華, 鹿玉理,“化學(xué)鍍鎳液中絡(luò)合劑濃度的快速測(cè)定”,電鍍與精飾, 1998, 20,(6):33-36.
37. 李懷納, 畢思偉, 劉汝濤, “N-亞水楊基亮氨酸3d金屬配位化合物的合成及薄層色譜與紫外光譜研究”,色譜, 1997,15(5):425－427.
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