郭俊明，男，1965年9月出生，漢族，江西省贛州市南康區(qū)人，中山醫(yī)科大學(xué)生物化學(xué)與分子生物學(xué)專業(yè)博士畢業(yè)。
個人經(jīng)歷
教育背景
郭俊明于1965年出生于江西贛州南康，后畢業(yè)于中山醫(yī)科大學(xué)，取得生物化學(xué)與分子生物學(xué)博士學(xué)位。
工作經(jīng)歷
郭俊明目前任職于寧波大學(xué)醫(yī)學(xué)院，擔(dān)任生物化學(xué)與分子生物學(xué)研究所所長。他還是浙江省“新世紀(jì)151人才工程”第二層次的人才，以及寧波市高校名師培養(yǎng)的對象。在教育方面，他是寧波大學(xué)生物化學(xué)與分子生物學(xué)碩士點(diǎn)的負(fù)責(zé)人，并且在上海交通大學(xué)醫(yī)學(xué)院擔(dān)任博士生導(dǎo)師。
近期研究成果
論文列表
郭俊明近期發(fā)表的重要論文包括：
1. Guo J, Jiang C, Wang Z, Lee HJ, Hu H, Malewicz B, Lee HJ, Lee JH, Baek NI, Jeong JH, Kim DK, Kang KS, Kim SH, Lu J. A novel class of pyranocoumarin anti-androgen receptor signaling compounds. Mol Cancer Ther. 2007;6(3):907-17. (SCI，IF 5.003)
2. Jiang C, Guo J, Wang Z, Xiao B, Lee HJ, Lee EO, Kim SH, Lu J. Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells. Breast Cancer Res. 2007;9(6):R77. （SCI，IF 5.052; Contributed equally）
3. Guo J*, Xiao B, Zhang X, Jin Z, Chen J, Qin L, Mao X, Shen G, Chen H, Liu Z. Combined use of positive and negative immunomagnetic isolation followed by real-time RT-PCR for detection of the circulating tumor cells in patients with colorectal cancers. J Mol Med. 2004;82(11):768-74. (SCI IF 4.37)
4. Xiao B, Guo J*, Miao Y, Jiang Z, Huan R, Zhang Y, Li D, Zhong J. Detection of miR-106a in gastric carcinoma and its clinical significance. Clin Chim Acta. 2009;400(1-2):97-102. （SCI IF 2.96）
5. Xiao B, Guo J*, Liu D, Zhang S. Aloe-emodin induces in vitro G2/M arrest and alkaline phosphatase activation in human oral cancer KB cells. Oral Oncol. 2007;43(9):905-10. （SCI IF 2.928）
6. Yao F, Guo JM*, Xu CF, Lou YL, Xiao BX, Zhou WH, Chen J, Hu YR, Liu Z, Hong GF. Detecting AFP mRNA in peripheral blood of the patients with hepatocellular carcinoma, liver cirrhosis and hepatitis. Clin Chim Acta. 2005;361(1-2):119-27. (SCI IF 2.96)
7. Guo J*, Miao Y, Xiao B, Huan R, Jiang Z, Meng D, Wang Y. Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. J Gastroenterol Hepatol. 2009;24(4):652-7. （SCI IF2.275）
8. Guo J*, Yao F, Lou Y, Xu C, Xiao B, Zhou W, Chen J, Hu Y, Liu Z. Detecting carcinoma cells in peripheral blood of patients with hepatocellular carcinoma by immunomagnetic beads and rt-PCR. J Clin Gastroenterol. 2007;41(8):783-8. （SCI IF 2.775）
9. Guo J*, Xiao B, Zhang S, Liu D, Liao Y, Sun Q. Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin. Cancer Biol Ther. 2007;6(1):85-8. （SCI IF 2.761）
10. Guo J*, Xiao B, Lou Y, Yan C, Zhan L, Wang D, Zhao W. Antitumor effects of all-trans-retinoic acid on cultured human pancreatic cancer cells. J Gastroenterol Hepatol. 2006 Feb;21(2):443-8. （SCI IF 2.275）
11. Guo J*, Xiao B, Jin Z, Qin L, Chen J, Chen H, Zhang X, Liu Z. Detection of cytokeratin 20 mRNA in the peripheral blood of patients with colorectal cancer by immunomagnetic bead enrichment and real-time reverse transcriptase-polymeras chain reaction. J Gastroenterol Hepatol. 2005;20(8):1279-84. (SCI IF 2.275)
12. Guo JM*, Xiao BX, Liu DH, Grant M, Zhang S, Lai YF, Guo YB, Liu Q. Biphasic effect of daidzein on cell growth of human colon cancer cells. Food Chem Toxicol. 2004;42(10):1641-6. (SCI IF 2.321)
13. Guo J*, Xiao B, Liu Q, Gong Z, Le Y. Suppression of C-myc Expression Associates with Anti-Proliferation of Aloe-Emodin on Gastric Cancer Cells. Cancer Investigation, 2008 26:4, 369 – 374 （SCI IF1.976）
14. Guo JM*, Xiao BX, Liu Q, Zhang S, Liu DH, Gong ZH. Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation. Acta Pharmacol Sin. 2007 Dec;28(12):1991-5. （SCI IF 1.676）
15. Lu J, Kim SH, Jiang C, Lee H, Guo J. Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents. Acta Pharmacol Sin. 2007;28(9):1365-72. （SCI IF 1.676）
16. Xiao B, Guo J*, Lou Y, Meng D, Zhao W, Zhang L, Yan C, Wang D. Inhibition of growth and increase of alkaline phosphatase activity in cultured human oral cancer cells by all-trans retinoic acid. Int J Oral Maxillofac Surg. 2006;35(7):643-8. （SCI IF 1.487）
17. Guo JM*, Xiao BX, Kang GZ, Liu DH, Chen H, Zhang S, Zhang XN. Suppression of telomerase activity and arrest at G1 phase in human cervical cancer HeLa cells by all-trans retinoic acid. Int J Gynecol Cancer. 2006 Jan-Feb;16(1):341-6. （SCI IF 1.932）
18. Malewicz B, Wang Z, Jiang C, Guo J, Cleary MP, Grande JP, Lü J. Enhancement of mammary carcinogenesis in two rodent models by silymarin dietary supplements. Carcinogenesis. 2006;27(9):1739-47. （SCI，IF 4.93）
19. Jiang C, Lee HJ, Li GX, Guo J, Malewicz B, Zhao Y, Lee EO, Lee HJ, Lee JH, Kim MS, Kim SH, Lu J. Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer. Cancer Res. 2006 Jan 1;66(1):453-63. (SCI，IF 7.514)
20. Guo JM*, Kang GZ, Xiao BX, Liu DH, Zhang S. Effect of daidzein on cell growth, cell cycle, and telomerase activity of human cervical cancer in vitro. Int J Gynecol Cancer. 2004;14(5):882-8. (SCI IF 1.932)
專著列表
郭俊明近期發(fā)表的重要專著包括：
1. 郭俊明主編。人體基因?qū)W。杭州。浙江科技出版社.2004.
科研獎項(xiàng)
郭俊明近期獲得的主要科研獎項(xiàng)包括：
1. 郭俊明、肖丙秀、劉東海、樓燕茹、賴依峰、張順、劉瓊、汪東輝、詹麗、嚴(yán)春紅. 浙江省科學(xué)技術(shù)獎。用現(xiàn)代分子生物學(xué)技術(shù)闡明常見營養(yǎng)成分的抗癌機(jī)制.2008年度。三等獎.
2. 郭俊明、肖丙秀、張新軍、陳健、樓燕茹、徐長風(fēng). 浙江省科技獎。外周血中微量消化系統(tǒng)惡性腫瘤細(xì)胞的分析及其臨床應(yīng)用.2006年度。三等獎.
3. 郭俊明、肖丙秀、張新軍、陳健、樓燕茹、徐長風(fēng). 浙江省醫(yī)藥衛(wèi)生科技創(chuàng)新獎。外周血中微量消化系統(tǒng)惡性腫瘤細(xì)胞的分析.2006年度。一等獎.
4. 郭俊明、肖丙秀、劉東海、賴依峰、張順、劉瓊. 浙江省高校科研成果獎。大豆苷原防治常見惡性腫瘤的研究.2007年度。一等獎.
5. 肖丙秀 郭俊明 樓燕茹 劉東海 汪東輝 詹麗 嚴(yán)春紅. 寧波市科技進(jìn)步獎。全反式維甲酸誘導(dǎo)分化實(shí)體瘤分子機(jī)制的系列研究.2008年度。三等獎.
參考資料 >
生物化學(xué)與分子生物學(xué)系.寧波大學(xué)醫(yī)學(xué)部.2024-10-08
郭俊明:醫(yī)學(xué)是終身學(xué)習(xí)的學(xué)科.寧波大學(xué)醫(yī)學(xué)部基礎(chǔ)醫(yī)學(xué)院.2024-10-08
學(xué)校簡介.寧波大學(xué)研究生院.2024-10-08